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A porous cervical mucus plug leads to preterm birth induced by experimental vaginal infection in mice

During gestation, the cervical mucus plug (CMP) acts to seal the cervical canal. Pilot studies in humans have suggested that a porous CMP may increase the risk of uterine infection and preterm birth. We examined the gel-forming content of the mouse vagina and the CMP. We experimentally infected preg...

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Detalles Bibliográficos
Autores principales: Lacroix, Guillaume, Gouyer, Valérie, Rocher, Mylène, Gottrand, Frédéric, Desseyn, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218384/
https://www.ncbi.nlm.nih.gov/pubmed/35754724
http://dx.doi.org/10.1016/j.isci.2022.104526