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Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review

BACKGROUND: An emerging strategy to increase deceased organ donation is to use dedicated donation physicians to champion organ donation. We sought to conduct a systematic review of the effectiveness of donation physicians in improving organ donation outcomes. OBJECTIVE: A systematic review was condu...

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Autores principales: Squires, Janet E., Aloisio, Laura D., Santos, Wilmer John, Cho-Young, Danielle, Taljaard, Monica, Gritters, Nills, Dhanani, Sonny, Knoll, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218440/
https://www.ncbi.nlm.nih.gov/pubmed/35756331
http://dx.doi.org/10.1177/20543581221107751
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author Squires, Janet E.
Aloisio, Laura D.
Santos, Wilmer John
Cho-Young, Danielle
Taljaard, Monica
Gritters, Nills
Dhanani, Sonny
Knoll, Gregory
author_facet Squires, Janet E.
Aloisio, Laura D.
Santos, Wilmer John
Cho-Young, Danielle
Taljaard, Monica
Gritters, Nills
Dhanani, Sonny
Knoll, Gregory
author_sort Squires, Janet E.
collection PubMed
description BACKGROUND: An emerging strategy to increase deceased organ donation is to use dedicated donation physicians to champion organ donation. We sought to conduct a systematic review of the effectiveness of donation physicians in improving organ donation outcomes. OBJECTIVE: A systematic review was conducted following Cochrane principles. MEDLINE, Embase, and CINHAL databases were searched from inception to March 26, 2020. METHODS: Quantitative studies examining the effects of donation physicians on all deceased organ donation outcomes were considered for inclusion. Review articles, editorials and opinion articles, and case studies were excluded. Study selection was completed independently by 2 team members; all discrepancies were resolved by consensus. Two team members independently extracted data from studies. RESULTS: A total of 1017 studies were screened, and 12 met inclusion criteria. Included studies were published between 1994 and 2019. Half used an interrupted time series design (n = 6; 50%), 3 (25%) were cohort studies, and 3 (25%) used a before-and-after study design. Outcomes (reported in greater than 50% of included articles) included consent/refusal rate (n = 8; 67%), number of potential donors (n = 7; 58%), and number of actual donors (n = 7; 58%). Across studies and design types, there was an increase in potential organ donors ranging from 8% to 143% (Mdn = 33%), an increase in actual organ donors from 15% to 113% (Mdn = 27%), an increase in donor consent rate from −3% to 258% (Mdn = 12%), and an increase in deceased donor transplants from 13% to 24% (Mdn = 19%) following the introduction of donation physicians. CONCLUSIONS: Donation physicians have the potential to significantly improve deceased organ donation. Further implementation and evaluation of donation physician programs is warranted. However, implementation should be undertaken with a clear plan for a methodologically rigorous evaluation of outcomes.
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spelling pubmed-92184402022-06-24 Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review Squires, Janet E. Aloisio, Laura D. Santos, Wilmer John Cho-Young, Danielle Taljaard, Monica Gritters, Nills Dhanani, Sonny Knoll, Gregory Can J Kidney Health Dis Original Basic Research BACKGROUND: An emerging strategy to increase deceased organ donation is to use dedicated donation physicians to champion organ donation. We sought to conduct a systematic review of the effectiveness of donation physicians in improving organ donation outcomes. OBJECTIVE: A systematic review was conducted following Cochrane principles. MEDLINE, Embase, and CINHAL databases were searched from inception to March 26, 2020. METHODS: Quantitative studies examining the effects of donation physicians on all deceased organ donation outcomes were considered for inclusion. Review articles, editorials and opinion articles, and case studies were excluded. Study selection was completed independently by 2 team members; all discrepancies were resolved by consensus. Two team members independently extracted data from studies. RESULTS: A total of 1017 studies were screened, and 12 met inclusion criteria. Included studies were published between 1994 and 2019. Half used an interrupted time series design (n = 6; 50%), 3 (25%) were cohort studies, and 3 (25%) used a before-and-after study design. Outcomes (reported in greater than 50% of included articles) included consent/refusal rate (n = 8; 67%), number of potential donors (n = 7; 58%), and number of actual donors (n = 7; 58%). Across studies and design types, there was an increase in potential organ donors ranging from 8% to 143% (Mdn = 33%), an increase in actual organ donors from 15% to 113% (Mdn = 27%), an increase in donor consent rate from −3% to 258% (Mdn = 12%), and an increase in deceased donor transplants from 13% to 24% (Mdn = 19%) following the introduction of donation physicians. CONCLUSIONS: Donation physicians have the potential to significantly improve deceased organ donation. Further implementation and evaluation of donation physician programs is warranted. However, implementation should be undertaken with a clear plan for a methodologically rigorous evaluation of outcomes. SAGE Publications 2022-06-21 /pmc/articles/PMC9218440/ /pubmed/35756331 http://dx.doi.org/10.1177/20543581221107751 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Basic Research
Squires, Janet E.
Aloisio, Laura D.
Santos, Wilmer John
Cho-Young, Danielle
Taljaard, Monica
Gritters, Nills
Dhanani, Sonny
Knoll, Gregory
Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title_full Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title_fullStr Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title_full_unstemmed Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title_short Impact of Donation Physicians on Deceased Organ Donation: A Systematic Review
title_sort impact of donation physicians on deceased organ donation: a systematic review
topic Original Basic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218440/
https://www.ncbi.nlm.nih.gov/pubmed/35756331
http://dx.doi.org/10.1177/20543581221107751
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