Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

Brown adipose tissue (BAT) has a role in maintaining systemic metabolic health in rodents and humans. Here, we show that metabolic stress induces BAT to produce coagulation factors, which then—together with molecules derived from the circulation—promote BAT dysfunction and systemic glucose intoleran...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuka, Shimizu, Ippei, Yoshida, Yohko, Ikegami, Ryutaro, Suda, Masayoshi, Katsuumi, Goro, Fujiki, Shinya, Ozaki, Kazuyuki, Abe, Manabu, Sakimura, Kenji, Okuda, Shujiro, Hayano, Toshiya, Nakamura, Kazuhiro, Walsh, Kenneth, Jespersen, Naja Zenius, Nielsen, Søren, Scheele, Camilla, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218513/
https://www.ncbi.nlm.nih.gov/pubmed/35754738
http://dx.doi.org/10.1016/j.isci.2022.104547

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