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Current Advances in CETSA

Knowing that the drug candidate binds to its intended target is a vital part of drug discovery. Thus, several labeled and label-free methods have been developed to study target engagement. In recent years, the cellular thermal shift assay (CETSA) with its variations has been widely adapted to drug d...

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Detalles Bibliográficos
Autor principal: Tolvanen, Tuomas Aleksi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218591/
https://www.ncbi.nlm.nih.gov/pubmed/35755818
http://dx.doi.org/10.3389/fmolb.2022.866764