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Ferrostatin-1 alleviates oxalate-induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis

The present study aimed to evaluate the role and mechanism of ferrostatin-1 (Fer-1) in oxalate (Ox)-induced renal tubular epithelial cell injury, fibrosis, and calcium oxalate (CaOx) stone formation. A CaOx model in mice kidneys was established via intraperitoneal injection of 80 mg/kg glyoxylic aci...

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Detalles Bibliográficos
Autores principales: Xie, Jinna, Ye, Zehua, Li, Lei, Xia, Yuqi, Yuan, Run, Ruan, Yuan, Zhou, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218727/
https://www.ncbi.nlm.nih.gov/pubmed/35703358
http://dx.doi.org/10.3892/mmr.2022.12772