Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)

Carcinogenesis of Structural Variations in Human Cancer In article number 2200818, Hebing Chen, Chengfeng Wang, and co‐workers report carcinogenesis of structural variations (SVs) focusing on their dynamic interplay with three‐dimensional (3D) genome organization with multi‐omics strategies integrat...

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Autores principales: Du, Yongxing, Gu, Zongting, Li, Zongze, Yuan, Zan, Zhao, Yue, Zheng, Xiaohao, Bo, Xiaochen, Chen, Hebing, Wang, Chengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218759/
http://dx.doi.org/10.1002/advs.202270113
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author Du, Yongxing
Gu, Zongting
Li, Zongze
Yuan, Zan
Zhao, Yue
Zheng, Xiaohao
Bo, Xiaochen
Chen, Hebing
Wang, Chengfeng
author_facet Du, Yongxing
Gu, Zongting
Li, Zongze
Yuan, Zan
Zhao, Yue
Zheng, Xiaohao
Bo, Xiaochen
Chen, Hebing
Wang, Chengfeng
author_sort Du, Yongxing
collection PubMed
description Carcinogenesis of Structural Variations in Human Cancer In article number 2200818, Hebing Chen, Chengfeng Wang, and co‐workers report carcinogenesis of structural variations (SVs) focusing on their dynamic interplay with three‐dimensional (3D) genome organization with multi‐omics strategies integrating long‐read single‐molecule real‐time (SMRT) sequencing and high‐throughput chromosome conformation capture (Hi‐C) technique in deadly human pancreatic cancer. This work provides a genome‐wide prospects of SVs and 3D genome, and expand current understanding of tumorigenesis, which might facilitate the identification of novel prognostic markers or therapeutic targets. [Image: see text]
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spelling pubmed-92187592022-06-29 Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022) Du, Yongxing Gu, Zongting Li, Zongze Yuan, Zan Zhao, Yue Zheng, Xiaohao Bo, Xiaochen Chen, Hebing Wang, Chengfeng Adv Sci (Weinh) Inside Front Cover Carcinogenesis of Structural Variations in Human Cancer In article number 2200818, Hebing Chen, Chengfeng Wang, and co‐workers report carcinogenesis of structural variations (SVs) focusing on their dynamic interplay with three‐dimensional (3D) genome organization with multi‐omics strategies integrating long‐read single‐molecule real‐time (SMRT) sequencing and high‐throughput chromosome conformation capture (Hi‐C) technique in deadly human pancreatic cancer. This work provides a genome‐wide prospects of SVs and 3D genome, and expand current understanding of tumorigenesis, which might facilitate the identification of novel prognostic markers or therapeutic targets. [Image: see text] John Wiley and Sons Inc. 2022-06-23 /pmc/articles/PMC9218759/ http://dx.doi.org/10.1002/advs.202270113 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Front Cover
Du, Yongxing
Gu, Zongting
Li, Zongze
Yuan, Zan
Zhao, Yue
Zheng, Xiaohao
Bo, Xiaochen
Chen, Hebing
Wang, Chengfeng
Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title_full Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title_fullStr Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title_full_unstemmed Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title_short Dynamic Interplay between Structural Variations and 3D Genome Organization in Pancreatic Cancer (Adv. Sci. 18/2022)
title_sort dynamic interplay between structural variations and 3d genome organization in pancreatic cancer (adv. sci. 18/2022)
topic Inside Front Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218759/
http://dx.doi.org/10.1002/advs.202270113
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