Cargando…

Principal component analysis of early immune cell dynamics during pembrolizumab treatment of advanced urothelial carcinoma

Immune checkpoint inhibitors have been approved as second-line therapy for patients with advanced urothelial carcinoma (UC). However, which patients will obtain clinical benefit remains to be determined. To identify predictive biomarkers for the pembrolizumab (PEM) response early during treatment, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teshima, Taro, Kobayashi, Yukari, Kawai, Taketo, Kushihara, Yoshihiro, Nagaoka, Koji, Miyakawa, Jimpei, Akiyama, Yoshiyuki, Yamada, Yuta, Sato, Yusuke, Yamada, Daisuke, Tanaka, Nobuyuki, Tsunoda, Tatsuhiko, Kume, Haruki, Kakimi, Kazuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219027/ https://www.ncbi.nlm.nih.gov/pubmed/35765279 http://dx.doi.org/10.3892/ol.2022.13384

Ejemplares similares

A case of miliary tuberculosis following transurethral surgery and prostate biopsy after intravesical Bacillus Calmette–Guerin immunotherapy
por: Kurokawa, Yoshiaki, et al.
Publicado: (2021)

Comparison of full-dose gemcitabine/cisplatin, dose-reduced gemcitabine/cisplatin, and gemcitabine/carboplatin in real-world patients with advanced urothelial carcinoma
por: Sugimoto, Kazuma, et al.
Publicado: (2022)

The prognostic value of PD‐L1 expression in upper tract urothelial carcinoma varies according to platelet count
por: Miyama, Yu, et al.
Publicado: (2018)

The association between the parameters of uroflowmetry and lower urinary tract symptoms in prostate cancer patients after robot-assisted radical prostatectomy
por: Takeshima, Yuta, et al.
Publicado: (2022)

Clinical significance and risk factors of International Society of Urological Pathology (ISUP) grade upgrading in prostate cancer patients undergoing robot-assisted radical prostatectomy
por: Takeshima, Yuta, et al.
Publicado: (2021)

Improved survival in real‐world patients with advanced urothelial carcinoma: A multicenter propensity score‐matched cohort study comparing a period before the introduction of pembrolizumab (2003–2011) and a more recent period (2016–2020)
por: Taguchi, Satoru, et al.
Publicado: (2022)

Clinical significance and risk factors of urethrovesical anastomotic urinary leakage following robot-assisted radical prostatectomy: a multi-institutional study
por: Kakutani, Shigenori, et al.
Publicado: (2021)

Low hemoglobin and PSA kinetics are prognostic factors of overall survival in metastatic castration-resistant prostate cancer patients
por: Hakozaki, Yuji, et al.
Publicado: (2023)

The ‘prostate-muscle index’: a simple pelvic cavity measurement predicting estimated blood loss and console time in robot-assisted radical prostatectomy
por: Kimura, Naoki, et al.
Publicado: (2022)

Early recurrence of bladder cancer in the colon after robot‐assisted radical cystectomy: Disappearance following dose‐dense methotrexate, vinblastine, doxorubicin and cisplatin treatment
por: Noda, Michio, et al.
Publicado: (2021)

Preservation of pelvic floor muscles contributes to early continence recovery after robot-assisted radical prostatectomy
por: Nakamura, Masaki, et al.
Publicado: (2022)

Time to castration resistance is a novel prognostic factor of cancer-specific survival in patients with nonmetastatic castration-resistant prostate cancer
por: Hakozaki, Yuji, et al.
Publicado: (2022)

Comparison of perioperative outcomes in elderly (age ≧ 75 years) vs. younger men undergoing robot-assisted radical prostatectomy
por: Yamada, Yuta, et al.
Publicado: (2020)

Prognostic significance of the albumin-to-globulin ratio for advanced urothelial carcinoma treated with pembrolizumab: a multicenter retrospective study
por: Taguchi, Satoru, et al.
Publicado: (2021)

Cumulative Incidence and Clinical Risk Factors of Radiation Cystitis after Radiotherapy for Prostate Cancer
por: Makino, Katsuhiro, et al.
Publicado: (2023)

Impact of immune-related adverse events on the therapeutic efficacy of pembrolizumab in urothelial carcinoma: a multicenter retrospective study using time-dependent analysis
por: Kawai, Taketo, et al.
Publicado: (2022)

Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis
por: Akiyama, Yoshiyuki, et al.
Publicado: (2021)

Deep Learning Models for Cystoscopic Recognition of Hunner Lesion in Interstitial Cystitis
por: Iwaki, Takuya, et al.
Publicado: (2023)

Two distinct phenotypes of immunologically hot gastric cancer subtypes
por: Saito, Noriyuki, et al.
Publicado: (2021)

A novel scoring method based on RNA‐Seq immunograms describing individual cancer‐immunity interactions
por: Kobayashi, Yukari, et al.
Publicado: (2020)

Selection of RNA-based evaluation methods for tumor microenvironment by comparing with histochemical and flow cytometric analyses in gastric cancer
por: Saito, Noriyuki, et al.
Publicado: (2022)

Left–right reversal of the testes within the scrotum: An extremely rare variant of testicular ectopia
por: Kishitani, Kenjiro, et al.
Publicado: (2022)

Endovascular catheter arterial embolization effectively treats secondary hypertension and increased plasma B-type natriuretic peptide level accompanied by idiopathic renal arteriovenous fistula
por: Nishikimi, Reo, et al.
Publicado: (2020)

Efficacy and Safety of Low-dose Oral Prednisolone for Patients with Refractory Hunner-type Interstitial Cystitis
por: Akiyama, Yoshiyuki, et al.
Publicado: (2023)

Surgical Tolerability and Frailty in Elderly Patients Undergoing Robot-Assisted Radical Prostatectomy: A Narrative Review
por: Yamada, Yuta, et al.
Publicado: (2022)

Principal motion analysis of manual stretching techniques for the ankle joints
por: Yamada, Naomi, et al.
Publicado: (2020)

Novel operative technique of advancement urethral meatoplasty utilizing buccal mucosa for Vulvar Paget’s disease with urethral invasion: two case reports
por: Nakamura, Masaki, et al.
Publicado: (2021)

Th1/17 polarization and potential treatment by an anti-interferon-γ DNA aptamer in Hunner-type interstitial cystitis
por: Akiyama, Yoshiyuki, et al.
Publicado: (2023)

Effect of M2-like macrophages of the injured-kidney cortex on kidney cancer progression
por: Ishii, Taisuke, et al.
Publicado: (2022)

Efficacy of pembrolizumab rechallenge for metastatic urothelial carcinoma
por: Nishimura, Nobutaka, et al.
Publicado: (2022)

A rare case of de novo large cell neuroendocrine carcinoma of the prostate with long-term survival after cystoprostatectomy and androgen deprivation
por: Miyakawa, Jimpei, et al.
Publicado: (2018)

Quantification of the individual risk of each Gleason pattern, including tertiary Gleason pattern 5, after radical prostatectomy: development of the modified Gleason grade grouping (mGGG) model
por: Taguchi, Satoru, et al.
Publicado: (2020)

Dermatomyositis associated with prostate adenocarcinoma with neuroendocrine differentiation
por: Minagawa, Hideyuki, et al.
Publicado: (2021)

Surgical resection of retinoblastoma-associated bladder leiomyosarcoma during pregnancy: a case report
por: Hoshina, Hayato, et al.
Publicado: (2023)

Favorable response to pembrolizumab in granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma
por: Takeda, Hiroki, et al.
Publicado: (2021)

Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab
por: Kobayashi, Takashi, et al.
Publicado: (2020)

Adenoma-carcinoma Sequence in the Bladder After Augmentation Cystoplasty
por: Naito, Akihiro, et al.
Publicado: (2014)

Profile of pembrolizumab in the treatment of patients with unresectable or metastatic urothelial carcinoma
por: Inokuchi, Junichi, et al.
Publicado: (2019)

Complete response to pembrolizumab in recurrent nested variant of urothelial carcinoma
por: Fukuta, Kyotaro, et al.
Publicado: (2021)

Variant allele frequency changes in TP53 predict pembrolizumab response in patients with metastatic urothelial carcinoma
por: Hamada, Kazuki, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f12puo6j7f7i3u9ori4t9gou2b