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First-in-Class Star-Shaped Triazine Dendrimers Endowed with MMP-9 Inhibition and VEGF Suppression Capacity: Design, Synthesis, and Anticancer Evaluation

[Image: see text] Off-target side effects are major challenges hindering the clinical success of matrix metalloproteinase (MMP) inhibitors. Various targeting strategies revitalized MMP research to eliminate this drawback. Herein, we developed s-triazine-based dendrimeric architecture not only amenab...

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Detalles Bibliográficos
Autores principales: Haiba, Nesreen S., Khalil, Hosam H., Bergas, Ahmed, Abu-Serie, Marwa M., Khattab, Sherine N., Teleb, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219090/
https://www.ncbi.nlm.nih.gov/pubmed/35755386
http://dx.doi.org/10.1021/acsomega.2c01949