circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop

BACKGROUND: In recent years, an increasing number of studies have indicated that circular RNA plays crucial roles in regulating tumor development and chemoresistance. Using two high-throughput RNA sequence datasets, we previously found that circEXOC6B was downregulated in colon cancer. However, its...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaomin, Wang, Jianjun, Lin, Weihao, Yuan, Qinzi, Lu, Yanxia, Wang, Haowei, Chen, Yujia, Chen, Lixia, Dai, Peiling, Long, Huaicheng, Li, Xuenong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219196/
https://www.ncbi.nlm.nih.gov/pubmed/35739524
http://dx.doi.org/10.1186/s12943-022-01600-1

Ejemplares similares

Ejemplares similares