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Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure
BACKGROUND: Long-term exposure to fine particulate matter (PM(2.5)) increases susceptibility to chronic respiratory diseases, including inflammation and interstitial fibrosis. However, the regulatory mechanisms by which the immune response mediates the initiation of pulmonary fibrosis has yet to be...
Autores principales: | Zhang, Rui, Chen, Shen, Chen, Liping, Ye, Lizhu, Jiang, Yue, Peng, Hui, Guo, Zhanyu, Li, Miao, Jiang, Xinhang, Guo, Ping, Yu, Dianke, Zhang, Rong, Niu, Yujie, Zhuang, Yuan, Aschner, Michael, Zheng, Yuxin, Li, Daochuan, Chen, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219231/ https://www.ncbi.nlm.nih.gov/pubmed/35739565 http://dx.doi.org/10.1186/s12989-022-00483-w |
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