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Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

BACKGROUND: Long-term exposure to fine particulate matter (PM(2.5)) increases susceptibility to chronic respiratory diseases, including inflammation and interstitial fibrosis. However, the regulatory mechanisms by which the immune response mediates the initiation of pulmonary fibrosis has yet to be...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Chen, Shen, Chen, Liping, Ye, Lizhu, Jiang, Yue, Peng, Hui, Guo, Zhanyu, Li, Miao, Jiang, Xinhang, Guo, Ping, Yu, Dianke, Zhang, Rong, Niu, Yujie, Zhuang, Yuan, Aschner, Michael, Zheng, Yuxin, Li, Daochuan, Chen, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219231/
https://www.ncbi.nlm.nih.gov/pubmed/35739565
http://dx.doi.org/10.1186/s12989-022-00483-w

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