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A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana

We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) grou...

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Autores principales: Yang, Lawrence H., Eschliman, Evan L., Mehta, Haitisha, Misra, Supriya, Poku, Ohemaa B., Entaile, Patlo, Becker, Timothy D., Melese, Tadele, Brooks, Merrian J., Eisenberg, Marlene, Stockton, Melissa A., Choe, Karen, Tal, Danielle, Li, Tingyu, Go, Vivian F., Link, Bruce G., Rampa, Shathani, Jackson, Valerie W., Manyeagae, Gorata D., Arscott-Mills, Tonya, Goodman, Melody, Opondo, Philip R., Ho-Foster, Ari R., Blank, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219368/
https://www.ncbi.nlm.nih.gov/pubmed/35739534
http://dx.doi.org/10.1186/s12981-022-00454-3
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author Yang, Lawrence H.
Eschliman, Evan L.
Mehta, Haitisha
Misra, Supriya
Poku, Ohemaa B.
Entaile, Patlo
Becker, Timothy D.
Melese, Tadele
Brooks, Merrian J.
Eisenberg, Marlene
Stockton, Melissa A.
Choe, Karen
Tal, Danielle
Li, Tingyu
Go, Vivian F.
Link, Bruce G.
Rampa, Shathani
Jackson, Valerie W.
Manyeagae, Gorata D.
Arscott-Mills, Tonya
Goodman, Melody
Opondo, Philip R.
Ho-Foster, Ari R.
Blank, Michael B.
author_facet Yang, Lawrence H.
Eschliman, Evan L.
Mehta, Haitisha
Misra, Supriya
Poku, Ohemaa B.
Entaile, Patlo
Becker, Timothy D.
Melese, Tadele
Brooks, Merrian J.
Eisenberg, Marlene
Stockton, Melissa A.
Choe, Karen
Tal, Danielle
Li, Tingyu
Go, Vivian F.
Link, Bruce G.
Rampa, Shathani
Jackson, Valerie W.
Manyeagae, Gorata D.
Arscott-Mills, Tonya
Goodman, Melody
Opondo, Philip R.
Ho-Foster, Ari R.
Blank, Michael B.
author_sort Yang, Lawrence H.
collection PubMed
description We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = − 1.20; 95% CI − 1.99, − 0.39) and depressive symptoms (d = − 1.96; 95% CI − 2.89, − 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12981-022-00454-3.
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spelling pubmed-92193682022-06-23 A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana Yang, Lawrence H. Eschliman, Evan L. Mehta, Haitisha Misra, Supriya Poku, Ohemaa B. Entaile, Patlo Becker, Timothy D. Melese, Tadele Brooks, Merrian J. Eisenberg, Marlene Stockton, Melissa A. Choe, Karen Tal, Danielle Li, Tingyu Go, Vivian F. Link, Bruce G. Rampa, Shathani Jackson, Valerie W. Manyeagae, Gorata D. Arscott-Mills, Tonya Goodman, Melody Opondo, Philip R. Ho-Foster, Ari R. Blank, Michael B. AIDS Res Ther Brief Report We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = − 1.20; 95% CI − 1.99, − 0.39) and depressive symptoms (d = − 1.96; 95% CI − 2.89, − 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12981-022-00454-3. BioMed Central 2022-06-23 /pmc/articles/PMC9219368/ /pubmed/35739534 http://dx.doi.org/10.1186/s12981-022-00454-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Brief Report
Yang, Lawrence H.
Eschliman, Evan L.
Mehta, Haitisha
Misra, Supriya
Poku, Ohemaa B.
Entaile, Patlo
Becker, Timothy D.
Melese, Tadele
Brooks, Merrian J.
Eisenberg, Marlene
Stockton, Melissa A.
Choe, Karen
Tal, Danielle
Li, Tingyu
Go, Vivian F.
Link, Bruce G.
Rampa, Shathani
Jackson, Valerie W.
Manyeagae, Gorata D.
Arscott-Mills, Tonya
Goodman, Melody
Opondo, Philip R.
Ho-Foster, Ari R.
Blank, Michael B.
A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_full A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_fullStr A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_full_unstemmed A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_short A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_sort pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with hiv in botswana
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219368/
https://www.ncbi.nlm.nih.gov/pubmed/35739534
http://dx.doi.org/10.1186/s12981-022-00454-3
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