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Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aβ40-Iowa and Aβ40-Dutch Peptides

[Image: see text] Two distinct diseases are associated with the deposition of fibrillar amyloid-β (Aβ) peptides in the human brain in an age-dependent fashion. Alzheimer’s disease is primarily associated with parenchymal plaque deposition of Aβ42, while cerebral amyloid angiopathy (CAA) is associate...

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Detalles Bibliográficos
Autores principales:	Rajpoot, Jitika, Crooks, Elliot J., Irizarry, Brandon A., Amundson, Ashley, Van Nostrand, William E., Smith, Steven O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219409/ https://www.ncbi.nlm.nih.gov/pubmed/35666749 http://dx.doi.org/10.1021/acs.biochem.1c00781

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