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Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler

SIMPLE SUMMARY: Broiler chickens have been consumed widely in many countries around the world because they can fulfill the nutritional needs of humans from meat. Antibiotics have been used in the broiler diet to reduce poultry pathogens and promote growth performance, but the overuse of antibiotics...

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Autores principales: Mohamed, Taha M., Sun, Weizhong, Bumbie, Gifty Z., Dosoky, Waleed M., Rao, Zebin, Hu, Ping, Wu, Liuting, Tang, Zhiru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219452/
https://www.ncbi.nlm.nih.gov/pubmed/35739895
http://dx.doi.org/10.3390/ani12121558
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author Mohamed, Taha M.
Sun, Weizhong
Bumbie, Gifty Z.
Dosoky, Waleed M.
Rao, Zebin
Hu, Ping
Wu, Liuting
Tang, Zhiru
author_facet Mohamed, Taha M.
Sun, Weizhong
Bumbie, Gifty Z.
Dosoky, Waleed M.
Rao, Zebin
Hu, Ping
Wu, Liuting
Tang, Zhiru
author_sort Mohamed, Taha M.
collection PubMed
description SIMPLE SUMMARY: Broiler chickens have been consumed widely in many countries around the world because they can fulfill the nutritional needs of humans from meat. Antibiotics have been used in the broiler diet to reduce poultry pathogens and promote growth performance, but the overuse of antibiotics in the poultry industry has led to serious consequences for public health. Hence, probiotics are a safe and healthy alternative to antibiotics. Bacillus subtilis is a common probiotic bacteria supplement formulated as a healthy probiotic strain. This study aimed to investigate the effects of dietary supplementation of Bacillus subtilis on growth performance, relative organ weights, and serum biochemical indices. ABSTRACT: This study was conducted to investigate the effects of supplementing Bacillus subtilis and an antibiotic (Zinc bacitracin) in the diet of broilers on growth performance, organ weight, blood metabolites, and digestive enzymes of broiler chickens. A total of 600 1-d Arbor Acres broilers were randomly allotted to five treatments. Each treatment consisted of six replicates with four pens, and each pen had five birds. The chicks were fed (1) the basal diet (control), (2) the basal diet with 500 mg/kg Zinc bacitracin (APZ), (3) the basal diet with B. subtilis at 1 × 10(8) CFU/g (B.Sut-1), (4) the basal diet with B. subtilis at 3 × 10(8) CFU/g (B.Sut-3), and (5) the basal diet with B. subtilis at 5 × 10(8) CFU/g (B.Sut-5). The experiment lasted for 42 days. In this study, the supplementation of diets with B. subtilis (B.Sut-3 and B.Sut-5 groups) increased body weight gain from 1 to 21 days compared with control (p < 0.05). Additionally, the B.Sut-3 group had a significantly heavier bursa of Fabricius than control at 21 days (p < 0.05). Serum total protein, albumin, and high-density lipoprotein concentrations were increased in B.Sut-5 and APZ groups (p < 0.05) over the whole period. Serum low-density lipoprotein, very low-density lipoprotein, triglyceride, and total cholesterol concentrations were decreased in B.Sut-5 and APZ groups at 21 and 42 days (p < 0.05). Chicks in the B.Sut-5 and APZ groups had higher serum lipase, pepsin, and amylase activities (p < 0.05) at 21 and 42 days. From the results obtained from the study, it can be concluded that Bacillus subtilis ATCC19659 at 5 × 10(8) CFU/g could be applied as an alternative to antibiotics in poultry diets.
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spelling pubmed-92194522022-06-24 Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler Mohamed, Taha M. Sun, Weizhong Bumbie, Gifty Z. Dosoky, Waleed M. Rao, Zebin Hu, Ping Wu, Liuting Tang, Zhiru Animals (Basel) Article SIMPLE SUMMARY: Broiler chickens have been consumed widely in many countries around the world because they can fulfill the nutritional needs of humans from meat. Antibiotics have been used in the broiler diet to reduce poultry pathogens and promote growth performance, but the overuse of antibiotics in the poultry industry has led to serious consequences for public health. Hence, probiotics are a safe and healthy alternative to antibiotics. Bacillus subtilis is a common probiotic bacteria supplement formulated as a healthy probiotic strain. This study aimed to investigate the effects of dietary supplementation of Bacillus subtilis on growth performance, relative organ weights, and serum biochemical indices. ABSTRACT: This study was conducted to investigate the effects of supplementing Bacillus subtilis and an antibiotic (Zinc bacitracin) in the diet of broilers on growth performance, organ weight, blood metabolites, and digestive enzymes of broiler chickens. A total of 600 1-d Arbor Acres broilers were randomly allotted to five treatments. Each treatment consisted of six replicates with four pens, and each pen had five birds. The chicks were fed (1) the basal diet (control), (2) the basal diet with 500 mg/kg Zinc bacitracin (APZ), (3) the basal diet with B. subtilis at 1 × 10(8) CFU/g (B.Sut-1), (4) the basal diet with B. subtilis at 3 × 10(8) CFU/g (B.Sut-3), and (5) the basal diet with B. subtilis at 5 × 10(8) CFU/g (B.Sut-5). The experiment lasted for 42 days. In this study, the supplementation of diets with B. subtilis (B.Sut-3 and B.Sut-5 groups) increased body weight gain from 1 to 21 days compared with control (p < 0.05). Additionally, the B.Sut-3 group had a significantly heavier bursa of Fabricius than control at 21 days (p < 0.05). Serum total protein, albumin, and high-density lipoprotein concentrations were increased in B.Sut-5 and APZ groups (p < 0.05) over the whole period. Serum low-density lipoprotein, very low-density lipoprotein, triglyceride, and total cholesterol concentrations were decreased in B.Sut-5 and APZ groups at 21 and 42 days (p < 0.05). Chicks in the B.Sut-5 and APZ groups had higher serum lipase, pepsin, and amylase activities (p < 0.05) at 21 and 42 days. From the results obtained from the study, it can be concluded that Bacillus subtilis ATCC19659 at 5 × 10(8) CFU/g could be applied as an alternative to antibiotics in poultry diets. MDPI 2022-06-16 /pmc/articles/PMC9219452/ /pubmed/35739895 http://dx.doi.org/10.3390/ani12121558 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mohamed, Taha M.
Sun, Weizhong
Bumbie, Gifty Z.
Dosoky, Waleed M.
Rao, Zebin
Hu, Ping
Wu, Liuting
Tang, Zhiru
Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title_full Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title_fullStr Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title_full_unstemmed Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title_short Effect of Dietary Supplementation of Bacillus subtilis on Growth Performance, Organ Weight, Digestive Enzyme Activities, and Serum Biochemical Indices in Broiler
title_sort effect of dietary supplementation of bacillus subtilis on growth performance, organ weight, digestive enzyme activities, and serum biochemical indices in broiler
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219452/
https://www.ncbi.nlm.nih.gov/pubmed/35739895
http://dx.doi.org/10.3390/ani12121558
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