Deciphering the Role of Histone Modifications in Uterine Leiomyoma: Acetylation of H3K27 Regulates the Expression of Genes Involved in Proliferation, Cell Signaling, Cell Transport, Angiogenesis and Extracellular Matrix Formation

Uterine leiomyoma (UL) is a benign tumor arising from myometrium (MM) with a high prevalence and unclear pathology. Histone modifications are altered in tumors, particularly via histone acetylation which is correlated with gene activation. To identify if the acetylation of H3K27 is involved in UL pa...

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Detalles Bibliográficos
Autores principales: Carbajo-García, María Cristina, de Miguel-Gómez, Lucia, Juárez-Barber, Elena, Trelis, Alexandra, Monleón, Javier, Pellicer, Antonio, Flanagan, James M., Ferrero, Hortensia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219820/
https://www.ncbi.nlm.nih.gov/pubmed/35740301
http://dx.doi.org/10.3390/biomedicines10061279

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