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Low-Salt Diet Reduces Anti-CTLA4 Mediated Systemic Immune-Related Adverse Events while Retaining Therapeutic Efficacy against Breast Cancer

SIMPLE SUMMARY: Immunotherapy has transformed breast cancer treatment. However, ICI-induced systemic inflammatory immune-related adverse events (irAE) remain a major clinical challenge. In our current communication, using breast tumor models, we demonstrated that a low salt diet could reduce irAE de...

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Detalles Bibliográficos
Autores principales: Khandekar, Durga, Dahunsi, Debolanle O., Manzanera Esteve, Isaac V., Reid, Sonya, Rathmell, Jeffrey C., Titze, Jens, Tiriveedhi, Venkataswarup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219826/
https://www.ncbi.nlm.nih.gov/pubmed/35741331
http://dx.doi.org/10.3390/biology11060810