Cargando…

Epigenetic Studies for Evaluation of NPS Toxicity: Focus on Synthetic Cannabinoids and Cathinones

In the recent decade, numerous new psychoactive substances (NPSs) have been added to the illicit drug market. These are synthetized to mimic the effects of classic drugs of abuse (i.e., cannabis, cocaine, etc.), with the purpose of bypassing substance legislations and increasing the pharmacotoxicolo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mazdai, Leila, Fabbri, Matteo, Tirri, Micaela, Corli, Giorgia, Arfè, Raffaella, Marchetti, Beatrice, Bilel, Sabrine, Bergamin, Eva, Gaudio, Rosa Maria, Rubini, Michele, De-Giorgio, Fabio, Marti, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219842/ https://www.ncbi.nlm.nih.gov/pubmed/35740419 http://dx.doi.org/10.3390/biomedicines10061398

Ejemplares similares

Pharmaco-Toxicological Effects of Atypical Synthetic Cathinone Mephtetramine (MTTA) in Mice: Possible Reasons for Its Brief Appearance over NPSs Scene
por: Corli, Giorgia, et al.
Publicado: (2023)

Synthetic cannabinoid JWH-073 alters both acute behavior and in vivo/vitro electrophysiological responses in mice
por: Barbieri, Mario, et al.
Publicado: (2022)

The Old and the New: Cardiovascular and Respiratory Alterations Induced by Acute JWH-018 Administration Compared to Δ(9)-THC—A Preclinical Study in Mice
por: Marchetti, Beatrice, et al.
Publicado: (2023)

Sensorimotor Alterations Induced by Novel Fentanyl Analogs in Mice: Possible Impact on Human Driving Performances
por: Bilel, Sabrine, et al.
Publicado: (2023)

Behavioral and Pharmacokinetics Studies of N-Methyl-2-Aminoindane (NM2AI) in Mice: An Aminoindane Briefly Used in the Illicit Drug Market
por: Tirri, Micaela, et al.
Publicado: (2023)

Single Exposure to the Cathinones MDPV and α-PVP Alters Molecular Markers of Neuroplasticity in the Adult Mouse Brain
por: Caffino, Lucia, et al.
Publicado: (2021)

Effect of -NBOMe Compounds on Sensorimotor, Motor, and Prepulse Inhibition Responses in Mice in Comparison With the 2C Analogs and Lysergic Acid Diethylamide: From Preclinical Evidence to Forensic Implication in Driving Under the Influence of Drugs
por: Tirri, Micaela, et al.
Publicado: (2022)

MAM-2201 acute administration impairs motor, sensorimotor, prepulse inhibition, and memory functions in mice: a comparison with its analogue AM-2201
por: Corli, Giorgia, et al.
Publicado: (2023)

Acute DOB and PMA Administration Impairs Motor and Sensorimotor Responses in Mice and Causes Hallucinogenic Effects in Adult Zebrafish
por: Tirri, Micaela, et al.
Publicado: (2020)

Acute Cardiovascular and Cardiorespiratory Effects of JWH-018 in Awake and Freely Moving Mice: Mechanism of Action and Possible Antidotal Interventions?
por: Marchetti, Beatrice, et al.
Publicado: (2023)

Worsening of the Toxic Effects of (±)Cis-4,4′-DMAR Following Its Co-Administration with (±)Trans-4,4′-DMAR: Neuro-Behavioural, Physiological, Immunohistochemical and Metabolic Studies in Mice
por: Tirri, Micaela, et al.
Publicado: (2021)

In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice
por: Tirri, Micaela, et al.
Publicado: (2022)

Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats
por: Bilel, Sabrine, et al.
Publicado: (2019)

Evaluation of Cytotoxic and Mutagenic Effects of the Synthetic Cathinones Mexedrone, α-PVP and α-PHP
por: Lenzi, Monia, et al.
Publicado: (2021)

Effect of Repeated Administration of ɣ-Valerolactone (GVL) and GHB in the Mouse: Neuroadaptive Changes of the GHB and GABAergic System
por: Frisoni, Paolo, et al.
Publicado: (2023)

Synthetic Cannabinoids and Cathinones Cardiotoxicity: Facts andPerspectives
por: Radaelli, Davide, et al.
Publicado: (2021)

Genotoxic Properties of Synthetic Cannabinoids on TK6 Human Cells by Flow Cytometry
por: Lenzi, Monia, et al.
Publicado: (2020)

In Vitro and In Vivo Pharmaco-Toxicological Characterization of 1-Cyclohexyl-x-methoxybenzene Derivatives in Mice: Comparison with Tramadol and PCP
por: Bilel, Sabrine, et al.
Publicado: (2021)

Comprehensive review of the detection methods for synthetic cannabinoids and cathinones
por: Namera, Akira, et al.
Publicado: (2015)

Metabolism study and toxicological determination of mephtetramine in biological samples by liquid chromatography coupled with high‐resolution mass spectrometry
por: Odoardi, Sara, et al.
Publicado: (2021)

Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe
por: Miliano, Cristina, et al.
Publicado: (2019)

Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health
por: Weinstein, Aviv M., et al.
Publicado: (2017)

Synthetic cathinone abuse
por: Capriola, Michael
Publicado: (2013)

Abuse of Synthetic Cannabinoids and Cathinones in a Patient on Buprenorphine-Naloxone Treatment: A Case Report
por: Awasthi, Harshal
Publicado: (2023)

Novel Synthetic Opioids: The Pathologist’s Point of View
por: Frisoni, Paolo, et al.
Publicado: (2018)

Application of Forensic DNA Phenotyping for Prediction of Eye, Hair and Skin Colour in Highly Decomposed Bodies
por: Fabbri, Matteo, et al.
Publicado: (2023)

New Synthetic Cathinones and Phenylethylamine Derivatives Analysis in Hair: A Review
por: Bolcato, Vittorio, et al.
Publicado: (2021)

Toxicological Analysis of Intoxications with Synthetic Cathinones
por: Pieprzyca, Ewelina, et al.
Publicado: (2021)

Synthetic cathinone (α-pyrrolidinohexanophenone): an emerging threat
por: Rosello-Molina, V., et al.
Publicado: (2022)

Neuropsychiatric effects of Synthetic Cathinones - a review
por: Mendes Coelho, J., et al.
Publicado: (2023)

The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative
por: Kolaczynska, Karolina E., et al.
Publicado: (2021)

Synthetic Cathinones: A New Public Health Problem
por: Karila, Laurent, et al.
Publicado: (2015)

Flakka: New Dangerous Synthetic Cathinone on the Drug Scene
por: Patocka, Jiri, et al.
Publicado: (2020)

Discriminative-Stimulus Effects of Synthetic Cathinones in Squirrel Monkeys
por: Wakeford, Alison G P, et al.
Publicado: (2021)

Synthetic Cathinones and Neurotoxicity Risks: A Systematic Review
por: Daziani, Gloria, et al.
Publicado: (2023)

Metabolic stability and metabolite profiling of emerging synthetic cathinones
por: Lopes, Rita P., et al.
Publicado: (2023)

Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice
por: Ossato, Andrea, et al.
Publicado: (2017)

Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats
por: Grecco, Gregory G., et al.
Publicado: (2018)

MON-146 Prolonged Hypoglycemia in the Setting of Synthetic Cathinone Abuse
por: Ramirez Berlioz, Ana, et al.
Publicado: (2019)

Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods
por: Almeida, Ana Sofia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_krv6lnr2knfnjklu130t1a7ajh