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Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response to solar UV. The quantitation of eumelanin an...

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Detalles Bibliográficos
Autores principales:	Upadhyay, Parth R., Starner, Renny J., Swope, Viki B., Wakamatsu, Kazumasa, Ito, Shosuke, Abdel-Malek, Zalfa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219903/ https://www.ncbi.nlm.nih.gov/pubmed/35740103 http://dx.doi.org/10.3390/antiox11061204

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