Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation

Exosomes/microvesicles originate from multivesicular bodies that allow the secretion of endolysosome components out of the cell. In the present work, we investigated the effects of rottlerin, a polyphenol, on exosome/microvesicle secretion in a model of intracellular lipid trafficking impairment, an...

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Detalles Bibliográficos
Autores principales: Molina, Yessenia L., García-Seisdedos, David, Babiy, Bohdan, Lerma, Milagros, Martínez-Botas, Javier, Casarejos, María J., Vallejo, María T., Gómez-Coronado, Diego, Lasunción, Miguel A., Pastor, Óscar, Busto, Rebeca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219951/
https://www.ncbi.nlm.nih.gov/pubmed/35740338
http://dx.doi.org/10.3390/biomedicines10061316

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