Reprogrammed CD8(+) T-Lymphocytes Isolated from Bone Marrow Have Anticancer Potential in Lung Cancer

CD8(+) T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes largely limits the effectiveness of therapy. In this study, reprogrammed T-lymphocytes used MEK inhi...

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Detalles Bibliográficos
Autores principales: Skurikhin, Evgenii G., Pershina, Olga, Ermakova, Natalia, Pakhomova, Angelina, Widera, Darius, Zhukova, Mariia, Pan, Edgar, Sandrikina, Lubov, Kogai, Lena, Kushlinskii, Nikolai, Morozov, Sergey G., Kubatiev, Aslan, Dygai, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219954/
https://www.ncbi.nlm.nih.gov/pubmed/35740471
http://dx.doi.org/10.3390/biomedicines10061450

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