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Bioenergetic and Autophagic Characterization of Skin Fibroblasts from C9orf72 Patients

The objective of this study is to describe the alterations occurring during the neurodegenerative process in skin fibroblast cultures from C9orf72 patients. We characterized the oxidative stress, autophagy flux, small ubiquitin-related protein SUMO2/3 levels as well as the mitochondrial function in...

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Detalles Bibliográficos
Autores principales: Alvarez-Mora, Maria Isabel, Garrabou, Gloria, Barcos, Tamara, Garcia-Garcia, Francisco, Grillo-Risco, Ruben, Peruga, Emma, Gort, Laura, Borrego-Écija, Sergi, Sanchez-Valle, Raquel, Canto-Santos, Judith, Navarro-Navarro, Paula, Rodriguez-Revenga, Laia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219955/
https://www.ncbi.nlm.nih.gov/pubmed/35740026
http://dx.doi.org/10.3390/antiox11061129