Cargando…

Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of “PCOS Males”

First-degree male relatives of polycystic ovary syndrome (PCOS) sufferers can develop metabolic abnormalities evidenced by elevated circulating cholesterol and triglycerides, suggestive of a male PCOS equivalent. Similarly, male sheep overexposed to excess androgens in fetal life develop dyslipidaem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Siemienowicz, Katarzyna J., Filis, Panagiotis, Thomas, Jennifer, Fowler, Paul A., Duncan, W. Colin, Rae, Mick T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220073/ https://www.ncbi.nlm.nih.gov/pubmed/35740312 http://dx.doi.org/10.3390/biomedicines10061291

Ejemplares similares

Fetal androgen exposure is a determinant of adult male metabolic health
por: Siemienowicz, Katarzyna J., et al.
Publicado: (2019)

Early pregnancy maternal progesterone administration alters pituitary and testis function and steroid profile in male fetuses
por: Siemienowicz, Katarzyna J., et al.
Publicado: (2020)

In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis
por: Connolly, Fiona, et al.
Publicado: (2015)

Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion
por: Ramaswamy, S., et al.
Publicado: (2016)

Mitochondrial Dysfunction in PCOS: Insights into Reproductive Organ Pathophysiology
por: Siemers, Kyle M., et al.
Publicado: (2023)

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)
por: Rae, Mick, et al.
Publicado: (2013)

Nutrient transporter expression in both the placenta and fetal liver are affected by maternal smoking
por: Walker, Natasha, et al.
Publicado: (2019)

Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome
por: Siemienowicz, Katarzyna, et al.
Publicado: (2020)

The Local Effects of Ovarian Diathermy in an Ovine Model of Polycystic Ovary Syndrome
por: Connolly, Fiona, et al.
Publicado: (2014)

Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation
por: Duncan, W. Colin, et al.
Publicado: (2023)

The prevalence of thyroid dysfunction and hyperprolactinemia in women with PCOS
por: van der Ham, Kim, et al.
Publicado: (2023)

Metabolic PCOS Features Are Ameliorated by Mitochondrial Uncoupler BAM15 in a PCOS Mouse Model
por: Paris, Valentina Rodriguez, et al.
Publicado: (2021)

The ovine hepatic mitochondrial proteome: Understanding seasonal weight loss tolerance in two distinct breeds
por: Miller, Blake A., et al.
Publicado: (2019)

Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response
por: Wheelhouse, Nick, et al.
Publicado: (2014)

OR35-01 Colonic Mitochondrial Dysfunction and Sub-acute Gastrointestinal Inflammation in Two Hyperandrogenemic Rodent Models of PCOS
por: Hoang, Ngoc, et al.
Publicado: (2023)

The complex metabolic interactions of liver tissue and hepatic exosome in PCOS mice at young and middle age
por: Gao, ShanHu, et al.
Publicado: (2022)

Sexual dysfunction in women with PCOS: a case control study
por: Pastoor, H, et al.
Publicado: (2023)

Ovine infectious keratoconjunctivitis in sheep: the farmer’s perspective
por: Williams, Helen J, et al.
Publicado: (2019)

Identification of an ancestral haplotype in the mitochondrial phylogeny of the ovine haplogroup B
por: Mereu, Paolo, et al.
Publicado: (2019)

The dysbiosis of ovine foot microbiome during the development and treatment of contagious ovine digital dermatitis
por: Duncan, J. S., et al.
Publicado: (2021)

FRI039 Endothelial Dysfunction Is Associated With Adiponectin And Leptin In Adolescents With PCOS
por: Gavryutina, Irina, et al.
Publicado: (2023)

Hepatic mitochondrial dysfunction in Friedreich Ataxia
por: Stüwe, Sven H, et al.
Publicado: (2011)

Chronic Low Grade Inflammation in Pathogenesis of PCOS
por: Rudnicka, Ewa, et al.
Publicado: (2021)

Inositols in PCOS
por: Kamenov, Zdravko, et al.
Publicado: (2020)

Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia
por: Phensy, Aarron, et al.
Publicado: (2017)

Advanced Glycation End Products: Link between Diet and Ovulatory Dysfunction in PCOS?
por: Garg, Deepika, et al.
Publicado: (2015)

Mitochondrial Dysfunction and Chronic Liver Disease
por: Zhang, Chunyan, et al.
Publicado: (2022)

Anti-Müllerian Hormone in Pathogenesis, Diagnostic and Treatment of PCOS
por: Rudnicka, Ewa, et al.
Publicado: (2021)

Ovine rotaviruses
por: Gazal, S., et al.
Publicado: (2011)

Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS
por: Donaldson, Nina M., et al.
Publicado: (2023)

Pre‐conditions for eliminating mitochondrial dysfunction and maintaining liver function after hepatic ischaemia reperfusion
por: Hu, Chenxia, et al.
Publicado: (2017)

Transcriptional Response of Ovine Lung to Infection with Jaagsiekte Sheep Retrovirus
por: Karagianni, Anna Eleonora, et al.
Publicado: (2019)

Dysfunctional mitochondrial bioenergetics and the pathogenesis of hepatic disorders
por: Auger, Christopher, et al.
Publicado: (2015)

Hepatitis C Virus-Induced Mitochondrial Dysfunctions
por: Brault, Charlène, et al.
Publicado: (2013)

Biomarker Profiles in Women with PCOS and PCOS Offspring; A Pilot Study
por: Daan, Nadine M. P., et al.
Publicado: (2016)

Beta endorphin in serum and follicular fluid of PCOS- and non-PCOS women
por: Jaschke, Nikolai, et al.
Publicado: (2018)

THU650 Prevalence Of Hyperandrogenemia, PCOS And Obesity In Mothers Of Daughters With PCOS
por: Cai, Jie, et al.
Publicado: (2023)

The radiographic anatomy of the normal ovine digit, the metacarpophalangeal and metatarsophalangeal joints
por: Duncan, Jennifer S., et al.
Publicado: (2012)

Low Expression of Mitofusin 1 Gene Leads to Mitochondrial Dysfunction and Embryonic Genome Activation Failure in Ovine-Bovine Inter-Species Cloned Embryos
por: Wu, Shanshan, et al.
Publicado: (2022)

Identification of catheter misplacement in early port CVC dysfunction
por: Mauri, Davide, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9arcgmc0oltpccqt3fq507sdfn