Cargando…

Antioxidant Properties of Cerium Oxide Nanoparticles Prevent Retinal Neovascular Alterations In Vitro and In Vivo

In this study, we investigated whether cerium oxide nanoparticles (CeO(2)-NPs), a promising antioxidant nanomaterial, may contrast retinal vascular alterations induced by oxidative damage in vitro and in vivo. For the in vivo experiments, the light damage (LD) animal model of Age-Related Macular Deg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tisi, Annamaria, Pulcini, Fanny, Carozza, Giulia, Mattei, Vincenzo, Flati, Vincenzo, Passacantando, Maurizio, Antognelli, Cinzia, Maccarone, Rita, Delle Monache, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220105/ https://www.ncbi.nlm.nih.gov/pubmed/35740031 http://dx.doi.org/10.3390/antiox11061133

Ejemplares similares

Nanoceria Particles Are an Eligible Candidate to Prevent Age-Related Macular Degeneration by Inhibiting Retinal Pigment Epithelium Cell Death and Autophagy Alterations
por: Tisi, Annamaria, et al.
Publicado: (2020)

Methylglyoxal-Dependent Glycative Stress Is Prevented by the Natural Antioxidant Oleuropein in Human Dental Pulp Stem Cells through Nrf2/Glo1 Pathway
por: Delle Monache, Simona, et al.
Publicado: (2021)

New Insights into Dose-Dependent Effects of Curcumin on ARPE-19 Cells
por: Carozza, Giulia, et al.
Publicado: (2022)

The Impact of Oxidative Stress on Blood-Retinal Barrier Physiology in Age-Related Macular Degeneration
por: Tisi, Annamaria, et al.
Publicado: (2021)

Up-regulation of pro-angiogenic pathways and induction of neovascularization by an acute retinal light damage
por: Tisi, A., et al.
Publicado: (2020)

Regenerative Potential of DPSCs and Revascularization: Direct, Paracrine or Autocrine Effect?
por: Mattei, Vincenzo, et al.
Publicado: (2021)

Gangliosides and Their Role in Multilineage Differentiation of Mesenchymal Stem Cells
por: Santilli, Francesca, et al.
Publicado: (2022)

mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening
por: Tisi, Annamaria, et al.
Publicado: (2022)

What Is Known about Theragnostic Strategies in Colorectal Cancer
por: Parisi, Alessandro, et al.
Publicado: (2021)

Dysregulation of Resolvin E1 Metabolism and Signaling in a Light-Damage Model of Age-Related Macular Degeneration
por: Tisi, Annamaria, et al.
Publicado: (2023)

Hypoxia Induces DPSC Differentiation versus a Neurogenic Phenotype by the Paracrine Mechanism
por: Delle Monache, Simona, et al.
Publicado: (2022)

Cerium Oxide Nanoparticles Reduce Microglial Activation and Neurodegenerative Events in Light Damaged Retina
por: Fiorani, Lavinia, et al.
Publicado: (2015)

Dental Pulp Stem Cells (DPSCs) and Tissue Regeneration: Mechanisms Mediated by Direct, Paracrine, or Autocrine Effects
por: Mattei, Vincenzo, et al.
Publicado: (2023)

10th Anniversary of Biomedicines—Advances in Mesenchymal Stem Cells
por: Mattei, Vincenzo, et al.
Publicado: (2023)

Lipid rafts mediate multilineage differentiation of human dental pulp-derived stem cells (DPSCs)
por: Santilli, Francesca, et al.
Publicado: (2023)

Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function
por: Antognelli, Cinzia, et al.
Publicado: (2017)

Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma
por: Colapietro, Alessandro, et al.
Publicado: (2021)

Cellular and Molecular Mechanisms Mediated by recPrP(C) Involved in the Neuronal Differentiation Process of Mesenchymal Stem Cells
por: Martellucci, Stefano, et al.
Publicado: (2019)

The Importance of Tumor Stem Cells in Glioblastoma Resistance to Therapy
por: Mattei, Vincenzo, et al.
Publicado: (2021)

Hypoxia-Mimetic CoCl(2) Agent Enhances Pro-Angiogenic Activities in Ovine Amniotic Epithelial Cells-Derived Conditioned Medium
por: Di Mattia, Miriam, et al.
Publicado: (2022)

KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
por: Antognelli, Cinzia, et al.
Publicado: (2018)

The Glyoxalase System Is a Novel Cargo of Amniotic Fluid Stem-Cell-Derived Extracellular Vesicles
por: Romani, Rita, et al.
Publicado: (2022)

The Importance of Stem Cells Isolated from Human Dental Pulp and Exfoliated Deciduous Teeth as Therapeutic Approach in Nervous System Pathologies
por: Candelise, Niccolò, et al.
Publicado: (2023)

Glyoxalases in Urological Malignancies
por: Antognelli, Cinzia, et al.
Publicado: (2018)

No Protective Effects of Hair Cells or Supporting Cells in Ototoxically Deafened Guinea Pigs upon Administration of BDNF
por: Tisi, Annamaria, et al.
Publicado: (2021)

A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte
por: Mezzasoma, Letizia, et al.
Publicado: (2017)

Intravitreal Avastin for Choroidal Neovascularization Associated with Stargardt-Like Retinal Abnormalities in Pseudoxanthoma Elasticum
por: Querques, Giuseppe, et al.
Publicado: (2010)

The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models
por: Gravina, Giovanni Luca, et al.
Publicado: (2019)

Glyoxalase 1−419C>A Variant Is Associated with Oxidative Stress: Implications in Prostate Cancer Progression
por: Antognelli, Cinzia, et al.
Publicado: (2013)

Metastatic Prostate Cancer Cells Secrete Methylglyoxal-Derived MG-H1 to Reprogram Human Osteoblasts into a Dedifferentiated, Malignant-like Phenotype: A Possible Novel Player in Prostate Cancer Bone Metastases
por: Antognelli, Cinzia, et al.
Publicado: (2021)

Glyoxalase-1-Dependent Methylglyoxal Depletion Sustains PD-L1 Expression in Metastatic Prostate Cancer Cells: A Novel Mechanism in Cancer Immunosurveillance Escape and a Potential Novel Target to Overcome PD-L1 Blockade Resistance
por: Antognelli, Cinzia, et al.
Publicado: (2021)

Choroidal and Retinal Imaging Biomarkers in Different Types of Macular Neovascularization
por: Toto, Lisa, et al.
Publicado: (2023)

Glyoxalase 1 sustains the metastatic phenotype of prostate cancer cells via EMT control
por: Antognelli, Cinzia, et al.
Publicado: (2018)

Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations
por: Antognelli, Cinzia, et al.
Publicado: (2020)

Retinal neovascularization and its regression on doxycycline in epidemic retinitis
por: Reddy, Subhakar, et al.
Publicado: (2020)

Targeting Neuroinflammation in Neovascular Retinal Diseases
por: Wang, Tianxi, et al.
Publicado: (2020)

Antioxidant Cerium Oxide Nanoparticles in Biology and Medicine
por: Nelson, Bryant C., et al.
Publicado: (2016)

TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B
por: Mezzasoma, Letizia, et al.
Publicado: (2013)

Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer
por: Antognelli, Cinzia, et al.
Publicado: (2019)

Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme
por: Antognelli, Cinzia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b2ni2sog6s2b9nq8u0gjc25dcj