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Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh
For supporting antibiotic stewardship interventions, the World Health Organization (WHO) classified antibiotics through the AWaRe (Access, Watch, and Reserve) classification. Inappropriate use of antimicrobials among hospital-admitted patients exposes them to the vulnerability of developing resistan...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220119/ https://www.ncbi.nlm.nih.gov/pubmed/35740216 http://dx.doi.org/10.3390/antibiotics11060810 |
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author | Rashid, Md. Mahbubur Akhtar, Zubair Chowdhury, Sukanta Islam, Md. Ariful Parveen, Shahana Ghosh, Probir Kumar Rahman, Aninda Khan, Zobaidul Haque Islam, Khaleda Debnath, Nitish Rahman, Mahmudur Chowdhury, Fahmida |
author_facet | Rashid, Md. Mahbubur Akhtar, Zubair Chowdhury, Sukanta Islam, Md. Ariful Parveen, Shahana Ghosh, Probir Kumar Rahman, Aninda Khan, Zobaidul Haque Islam, Khaleda Debnath, Nitish Rahman, Mahmudur Chowdhury, Fahmida |
author_sort | Rashid, Md. Mahbubur |
collection | PubMed |
description | For supporting antibiotic stewardship interventions, the World Health Organization (WHO) classified antibiotics through the AWaRe (Access, Watch, and Reserve) classification. Inappropriate use of antimicrobials among hospital-admitted patients exposes them to the vulnerability of developing resistant organisms which are difficult to treat. We aimed to describe the proportion of antibiotic use based on the WHO AWaRe classification in tertiary and secondary level hospitals in Bangladesh. A point prevalence survey (PPS) was conducted adapting the WHO PPS design in inpatients departments in 2021. Among the 1417 enrolled patients, 52% were female and 63% were from the 15–64 years age group. Nearly 78% of patients received at least one antibiotic during the survey period. Third-generation cephalosporins (44.6%), penicillins (12.3%), imidazoles (11.8%), aminoglycosides (7.2%), and macrolides (5.8%) were documented as highly used antibiotics. Overall, 64.0% of Watch, 35.6% of Access, and 0.1% of Reserve group antibiotics were used for treatment. The use of Watch group antibiotics was high in medicine wards (78.7%) and overall high use of Watch antibiotics was observed at secondary hospitals (71.5%) compared to tertiary hospitals (60.2%) (p-value of 0.000). Our PPS findings underscore the need for an urgent nationwide antibiotic stewardship program for physicians including the development and implementation of local guidelines and in-service training on antibiotic use. |
format | Online Article Text |
id | pubmed-9220119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92201192022-06-24 Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh Rashid, Md. Mahbubur Akhtar, Zubair Chowdhury, Sukanta Islam, Md. Ariful Parveen, Shahana Ghosh, Probir Kumar Rahman, Aninda Khan, Zobaidul Haque Islam, Khaleda Debnath, Nitish Rahman, Mahmudur Chowdhury, Fahmida Antibiotics (Basel) Article For supporting antibiotic stewardship interventions, the World Health Organization (WHO) classified antibiotics through the AWaRe (Access, Watch, and Reserve) classification. Inappropriate use of antimicrobials among hospital-admitted patients exposes them to the vulnerability of developing resistant organisms which are difficult to treat. We aimed to describe the proportion of antibiotic use based on the WHO AWaRe classification in tertiary and secondary level hospitals in Bangladesh. A point prevalence survey (PPS) was conducted adapting the WHO PPS design in inpatients departments in 2021. Among the 1417 enrolled patients, 52% were female and 63% were from the 15–64 years age group. Nearly 78% of patients received at least one antibiotic during the survey period. Third-generation cephalosporins (44.6%), penicillins (12.3%), imidazoles (11.8%), aminoglycosides (7.2%), and macrolides (5.8%) were documented as highly used antibiotics. Overall, 64.0% of Watch, 35.6% of Access, and 0.1% of Reserve group antibiotics were used for treatment. The use of Watch group antibiotics was high in medicine wards (78.7%) and overall high use of Watch antibiotics was observed at secondary hospitals (71.5%) compared to tertiary hospitals (60.2%) (p-value of 0.000). Our PPS findings underscore the need for an urgent nationwide antibiotic stewardship program for physicians including the development and implementation of local guidelines and in-service training on antibiotic use. MDPI 2022-06-16 /pmc/articles/PMC9220119/ /pubmed/35740216 http://dx.doi.org/10.3390/antibiotics11060810 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rashid, Md. Mahbubur Akhtar, Zubair Chowdhury, Sukanta Islam, Md. Ariful Parveen, Shahana Ghosh, Probir Kumar Rahman, Aninda Khan, Zobaidul Haque Islam, Khaleda Debnath, Nitish Rahman, Mahmudur Chowdhury, Fahmida Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title | Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title_full | Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title_fullStr | Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title_full_unstemmed | Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title_short | Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh |
title_sort | pattern of antibiotic use among hospitalized patients according to who access, watch, reserve (aware) classification: findings from a point prevalence survey in bangladesh |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220119/ https://www.ncbi.nlm.nih.gov/pubmed/35740216 http://dx.doi.org/10.3390/antibiotics11060810 |
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