Cargando…

Metabolic Profile and Pathological Alterations in the Muscle of Patients with Early-Stage Amyotrophic Lateral Sclerosis

Diverse biomarkers and pathological alterations have been found in muscle of patients with Amyotrophic lateral sclerosis (ALS), but the relation between such alterations and dysfunction in energetic metabolism remains to be investigated. We established the metabolome of muscle and serum of ALS patie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lanznaster, Débora, Bruno, Clément, Bourgeais, Jérôme, Emond, Patrick, Zemmoura, Ilyess, Lefèvre, Antoine, Reynier, Pascal, Eymieux, Sébastien, Blanchard, Emmanuelle, Vourc’h, Patrick, Andres, Christian R., Bakkouche, Salah Eddine, Herault, Olivier, Favard, Luc, Corcia, Philippe, Blasco, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220134/ https://www.ncbi.nlm.nih.gov/pubmed/35740329 http://dx.doi.org/10.3390/biomedicines10061307

Ejemplares similares

Aβ1-42 and Tau as Potential Biomarkers for Diagnosis and Prognosis of Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020)

TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2019)

Some CSF Kynurenine Pathway Intermediates Associated with Disease Evolution in Amyotrophic Lateral Sclerosis
por: Alarcan, Hugo, et al.
Publicado: (2021)

Conditioned Medium from Cells Overexpressing TDP-43 Alters the Metabolome of Recipient Cells
por: Hergesheimer, Rudolf, et al.
Publicado: (2020)

Metabolomics: A Tool to Understand the Impact of Genetic Mutations in Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020)

The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
por: Hergesheimer, Rudolf C, et al.
Publicado: (2019)

Study of Ubiquitin Pathway Genes in a French Population with Amyotrophic Lateral Sclerosis: Focus on HECW1 Encoding the E3 Ligase NEDL1
por: Haouari, Shanez, et al.
Publicado: (2023)

Is There a Role for Vitamin D in Amyotrophic Lateral Sclerosis? A Systematic Review and Meta-Analysis
por: Lanznaster, Débora, et al.
Publicado: (2020)

The Roles of NEDD4 Subfamily of HECT E3 Ubiquitin Ligases in Neurodevelopment and Neurodegeneration
por: Haouari, Shanez, et al.
Publicado: (2022)

Taking Advantages of Blood–Brain or Spinal Cord Barrier Alterations or Restoring Them to Optimize Therapy in ALS?
por: Alarcan, Hugo, et al.
Publicado: (2022)

(1)H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis
por: Blasco, Hélène, et al.
Publicado: (2010)

Correction: (1)H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis
por: Blasco, Hélène, et al.
Publicado: (2010)

Implication of Central Nervous System Barrier Impairment in Amyotrophic Lateral Sclerosis: Gender-Related Difference in Patients
por: Alarcan, Hugo, et al.
Publicado: (2023)

Dysregulations of Expression of Genes of the Ubiquitin/SUMO Pathways in an In Vitro Model of Amyotrophic Lateral Sclerosis Combining Oxidative Stress and SOD1 Gene Mutation
por: Dangoumau, Audrey, et al.
Publicado: (2021)

Metabolomics as a Crucial Tool to Develop New Therapeutic Strategies for Neurodegenerative Diseases
por: Lanznaster, Débora, et al.
Publicado: (2022)

The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls
por: Petillon, Camille, et al.
Publicado: (2019)

Metabolomics Biomarkers: A Strategy Toward Therapeutics Improvement in ALS
por: Lanznaster, Débora, et al.
Publicado: (2018)

Functional Anatomy of the Inferior Longitudinal Fasciculus: From Historical Reports to Current Hypotheses
por: Herbet, Guillaume, et al.
Publicado: (2018)

Lipidomics Reveals Cerebrospinal-Fluid Signatures of ALS
por: Blasco, H., et al.
Publicado: (2017)

NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity
por: Madji Hounoum, Blandine, et al.
Publicado: (2016)

Asymmetric Ensemble of Asymmetric U-Net Models for Brain Tumor Segmentation With Uncertainty Estimation
por: Rosas-Gonzalez, Sarahi, et al.
Publicado: (2021)

Iron Metabolism Disturbance in a French Cohort of ALS Patients
por: Veyrat-Durebex, Charlotte, et al.
Publicado: (2014)

SETMAR Shorter Isoform: A New Prognostic Factor in Glioblastoma
por: Lié, Oriane, et al.
Publicado: (2022)

The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism
por: Blasco, H., et al.
Publicado: (2020)

Evidence of a middle longitudinal fasciculus in the human brain from fiber dissection
por: Maldonado, Igor Lima, et al.
Publicado: (2013)

Rarity of microbial species: In search of reliable associations
por: Cougoul, Arnaud, et al.
Publicado: (2019)

How Can a Ketogenic Diet Improve Motor Function?
por: Veyrat-Durebex, Charlotte, et al.
Publicado: (2018)

Amyotrophic lateral sclerosis and the clinical potential of dexpramipexole
por: Corcia, Philippe, et al.
Publicado: (2012)

What Was the Set of Ubiquitin and Ubiquitin-Like Conjugating Enzymes in the Eukaryote Common Ancestor?
por: Michelle, Caroline, et al.
Publicado: (2009)

The importance of multiparasitism: examining the consequences of co-infections for human and animal health
por: Vaumourin, Elise, et al.
Publicado: (2015)

Relationship between Metabolomics Profile of Perilymph in Cochlear-Implanted Patients and Duration of Hearing Loss
por: Trinh, Thuy-Trân, et al.
Publicado: (2019)

A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis
por: Devos, David, et al.
Publicado: (2019)

The central role of the left inferior longitudinal fasciculus in the face‐name retrieval network
por: Burkhardt, Eléonor, et al.
Publicado: (2023)

Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis
por: Henriques, Alexandre, et al.
Publicado: (2017)

Author Correction: A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis
por: Devos, David, et al.
Publicado: (2020)

Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders
por: Desprez, Florence, et al.
Publicado: (2023)

Therapeutic antibodies – natural and pathological barriers and strategies to overcome them
por: Al Ojaimi, Yara, et al.
Publicado: (2022)

Current view and perspectives in amyotrophic lateral sclerosis
por: Mathis, Stéphane, et al.
Publicado: (2017)

Immediate-Early Modifications to the Metabolomic Profile of the Perilymph Following an Acoustic Trauma in a Sheep Model
por: Boullaud, Luc, et al.
Publicado: (2022)

Genetic variability in sporadic amyotrophic lateral sclerosis
por: Van Daele, Sien Hilde, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kd8kh61s1ivgec1e8oqvd265bk