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Uric Acid Reacts with Peroxidasin, Decreases Collagen IV Crosslink, Impairs Human Endothelial Cell Migration and Adhesion

Uric acid is considered the main substrate for peroxidases in plasma. The oxidation of uric acid by human peroxidases generates urate free radical and urate hydroperoxide, which might affect endothelial function and explain, at least in part, the harmful effects of uric acid on the vascular system....

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Detalles Bibliográficos
Autores principales:	Dempsey, Bianca, Cruz, Litiele Cezar, Mineiro, Marcela Franco, da Silva, Railmara Pereira, Meotti, Flavia Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220231/ https://www.ncbi.nlm.nih.gov/pubmed/35740014 http://dx.doi.org/10.3390/antiox11061117

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