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Pyruvate Dehydrogenase A1 Phosphorylated by Insulin Associates with Pyruvate Kinase M2 and Induces LINC00273 through Histone Acetylation

Insulin potently promotes cell proliferation and anabolic metabolism along with a reduction in blood glucose levels. Pyruvate dehydrogenase (PDH) plays a pivotal role in glucose metabolism. Insulin increase PDH activity by attenuating phosphorylated Ser293 PDH E1α (p-PDHA1) in normal liver tissue. I...

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Detalles Bibliográficos
Autores principales:	Hossain, Abu Jubayer, Islam, Rokibul, Kim, Jae-Gyu, Dogsom, Oyungerel, Cap, Kim Cuong, Park, Jae-Bong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220252/ https://www.ncbi.nlm.nih.gov/pubmed/35740278 http://dx.doi.org/10.3390/biomedicines10061256

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