Cargando…

Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation

SIMPLE SUMMARY: The skin epidermis is a stratified multilayered epithelium that provides a life-sustaining protective and defensive barrier for our body. The barrier machinery is established and maintained through a tightly regulated keratinocyte differentiation program. Under normal conditions, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Juan, Eming, Sabine A., Ding, Xiaolei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220260/ https://www.ncbi.nlm.nih.gov/pubmed/35741452 http://dx.doi.org/10.3390/biology11060931

Ejemplares similares

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling
por: Wang, Juan, et al.
Publicado: (2022)

mTOR regulates brain morphogenesis by mediating GSK3 signaling
por: Ka, Minhan, et al.
Publicado: (2014)

mTOR Signaling Cascade in Psoriatic Disease: Double Kinase mTOR Inhibitor a Novel Therapeutic Target
por: Raychaudhuri, Smriti K, et al.
Publicado: (2014)

Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Formation in Human Skin Equivalents
por: Mieremet, Arnout, et al.
Publicado: (2019)

Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis
por: Baskaran, Pranetha, et al.
Publicado: (2022)

mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis
por: Morrison, Meghan M., et al.
Publicado: (2015)

Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formation
por: Mieremet, Arnout, et al.
Publicado: (2019)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization and Barrier Formation
por: Hayez, Aurélie, et al.
Publicado: (2016)

Predominant Role of mTOR Signaling in Skin Diseases with Therapeutic Potential
por: Karagianni, Fani, et al.
Publicado: (2022)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Control of mTOR Signaling by Ubiquitin
por: Jiang, Yao, et al.
Publicado: (2019)

mTOR Signaling in Metabolism and Cancer
por: Huang, Shile
Publicado: (2020)

Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade
por: Maiese, Kenneth, et al.
Publicado: (2012)

Recent Updates on the Involvement of PI3K/AKT/mTOR Molecular Cascade in the Pathogenesis of Hyperproliferative Skin Disorders
por: Mercurio, Laura, et al.
Publicado: (2021)

Plasma polymerized bio-interface directs fibronectin adsorption and functionalization to enhance “epithelial barrier structure” formation via FN-ITG β1-FAK-mTOR signaling cascade
por: Chen, Shoucheng, et al.
Publicado: (2022)

Kaempferol promotes bone formation in part via the mTOR signaling pathway
por: Zhao, Jing, et al.
Publicado: (2019)

Autophagy Inhibits Inflammation via Down-Regulation of p38 MAPK/mTOR Signaling Cascade in Endothelial Cells
por: Zhou, Ling, et al.
Publicado: (2023)

AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1
por: Umanah, George K. E., et al.
Publicado: (2022)

T memory stem cell formation: Caveat mTOR
por: Fowler, Daniel H., et al.
Publicado: (2016)

All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells
por: Gamper, Christopher J., et al.
Publicado: (2012)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Flavonoids Targeting the mTOR Signaling Cascades in Cancer: A Potential Crosstalk in Anti-Breast Cancer Therapy
por: Hussain, Yaseen, et al.
Publicado: (2022)

The mTOR Signalling Pathway in Human Cancer
por: Pópulo, Helena, et al.
Publicado: (2012)

mTOR-dependent signalling in Alzheimer's disease
por: Pei, Jin-Jing, et al.
Publicado: (2008)

SYK Regulates mTOR Signaling in AML
por: Carnevale, Julia, et al.
Publicado: (2013)

Roles of mTOR Signaling in Brain Development
por: Lee, Da Yong
Publicado: (2015)

Signaling crosstalk between the mTOR complexes
por: Xie, Jianling, et al.
Publicado: (2014)

mTOR signaling in skeletal development and disease
por: Chen, Jianquan, et al.
Publicado: (2018)

Experimental Approaches in Delineating mTOR Signaling
por: Qian, Jiayi, et al.
Publicado: (2020)

Roles of mTOR Signaling in Tissue Regeneration
por: Wei, Xiangyong, et al.
Publicado: (2019)

Role of mTOR Signaling in Female Reproduction
por: Guo, Zaixin, et al.
Publicado: (2019)

mTOR Signaling Components in Tumor Mechanobiology
por: Gargalionis, Antonios N., et al.
Publicado: (2022)

mTOR Signaling in Metabolic Stress Adaptation
por: Wu, Cheng-Wei, et al.
Publicado: (2021)

The mTOR signaling pathway in cardiac aging
por: Dai, Dao-Fu, et al.
Publicado: (2023)

Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
por: Spormann, Luise, et al.
Publicado: (2020)

SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling
por: Li, Xiaoxue, et al.
Publicado: (2021)

Multitargeted Approach for the Optimization of Morphogenesis and Barrier Formation in Human Skin Equivalents
por: Mieremet, Arnout, et al.
Publicado: (2021)

mTOR signaling-related MicroRNAs and Cancer involvement
por: WANG, Ping, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qhfe6csk054dfrcnvjjup8lt4a