Cargando…
A new class of half-sandwich ruthenium complexes containing Biginelli hybrids: anticancer and anti-SARS-CoV-2 activities
In order to discover new dual-active agents, a series of novel Biginelli hybrids (tetrahydropyrimidines) and their ruthenium(II) complexes were synthesized. Newly synthesized compounds were characterized by IR, NMR, and X-ray techniques and investigated for their cytotoxic effect on human cancer cel...
Autores principales: | Janković, Nenad, Milović, Emilija, Jovanović, Jelena Đorović, Marković, Zoran, Vraneš, Milan, Stanojković, Tatjana, Matić, Ivana, Crnogorac, Marija Đorđić, Klisurić, Olivera, Cvetinov, Miroslav, Abbas Bukhari, Syed Nasir |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220501/ https://www.ncbi.nlm.nih.gov/pubmed/35752294 http://dx.doi.org/10.1016/j.cbi.2022.110025 |
Ejemplares similares
-
Synthesis, Characterization, and Biological Evaluation of Tetrahydropyrimidines: Dual-Activity and Mechanism of Action
por: Milović, Emilija, et al.
Publicado: (2022) -
Synthesis and Characterization of Dihydrouracil Analogs Utilizing Biginelli Hybrids
por: Bukhari, Syed Nasir Abbas, et al.
Publicado: (2022) -
Investigation of the radical scavenging potential of vanillin-based pyrido-dipyrimidines: experimental and in silico approach
por: Janković, Nenad, et al.
Publicado: (2023) -
Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment
por: Ristovski (Trifunović), Jovana, et al.
Publicado: (2020) -
In silico study of inhibitory capacity of sacubitril/valsartan toward neprilysin and angiotensin receptor
por: Jovanović, Jelena Đorović, et al.
Publicado: (2022)