High-Frequency Irreversible Electroporation (H-FIRE) Induced Blood–Brain Barrier Disruption Is Mediated by Cytoskeletal Remodeling and Changes in Tight Junction Protein Regulation

Glioblastoma is the deadliest malignant brain tumor. Its location behind the blood–brain barrier (BBB) presents a therapeutic challenge by preventing effective delivery of most chemotherapeutics. H-FIRE is a novel tumor ablation method that transiently disrupts the BBB through currently unknown mech...

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Detalles Bibliográficos
Autores principales: Partridge, Brittanie R., Kani, Yukitaka, Lorenzo, Melvin F., Campelo, Sabrina N., Allen, Irving C., Hinckley, Jonathan, Hsu, Fang-Chi, Verbridge, Scott S., Robertson, John L., Davalos, Rafael V., Rossmeisl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220673/
https://www.ncbi.nlm.nih.gov/pubmed/35740406
http://dx.doi.org/10.3390/biomedicines10061384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220673/
https://www.ncbi.nlm.nih.gov/pubmed/35740406
http://dx.doi.org/10.3390/biomedicines10061384

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