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Lactobacillus acidophilus Mitigates Osteoarthritis-Associated Pain, Cartilage Disintegration and Gut Microbiota Dysbiosis in an Experimental Murine OA Model

To test probiotic therapy for osteoarthritis (OA), we administered Lactobacillus acidophilus (LA) by oral gavage (2×/week) after induction of OA by partial medial meniscectomy (PMM). Pain was assessed by von Frey filament and hot plate testing. Joint pathology and pain markers were comprehensively a...

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Detalles Bibliográficos
Autores principales: O-Sullivan, InSug, Natarajan Anbazhagan, Arivarasu, Singh, Gurjit, Ma, Kaige, Green, Stefan J., Singhal, Megha, Wang, Jun, Kumar, Anoop, Dudeja, Pradeep K., Unterman, Terry G., Votta-Velis, Gina, Bruce, Benjamin, van Wijnen, Andre J., Im, Hee-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220766/
https://www.ncbi.nlm.nih.gov/pubmed/35740320
http://dx.doi.org/10.3390/biomedicines10061298