Cargando…
AKT, a Key Transmitter of HIF-1α and AR Signaling Pathways, Has a Critical Role in the Apigetrin-Mediated Anti-Cancer Effects in Prostate Cancer Cells
Apigetrin is a flavonoid glycoside phytochemical that is derived from various herbs and exhibits several beneficial biological activities, including anti-oxidant, anti-inflammatory, anti-obesity, and anti-cancer effects. In the present study, we elucidated the anti-cancer effect and targeting mechan...
Autores principales: | Lee, You-Kyung, Kim, Jung-Eun, Xu, Yinzhu, Han, Hengmin, Lee, Jae-Hyeon, Lee, Hyo-Jeong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220772/ https://www.ncbi.nlm.nih.gov/pubmed/35740392 http://dx.doi.org/10.3390/biomedicines10061370 |
Ejemplares similares
-
Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer
por: Xu, Yinzhu, et al.
Publicado: (2020) -
SPHK/HIF-1α Signaling Pathway Has a Critical Role in Chrysin-Induced Anticancer Activity in Hypoxia-Induced PC-3 Cells
por: Han, Hengmin, et al.
Publicado: (2022) -
Inhibition of Cell Proliferation and Cell Death by Apigetrin through Death Receptor-Mediated Pathway in Hepatocellular Cancer Cells
por: Bhosale, Pritam Bhagwan, et al.
Publicado: (2023) -
The HIF/PHF8/AR axis promotes prostate cancer progression
por: Tong, D, et al.
Publicado: (2016) -
Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α
por: Hadrich, Fatma, et al.
Publicado: (2018)