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Tumor-Suppressive Effect of Metformin via the Regulation of M2 Macrophages and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment of Colorectal Cancer

SIMPLE SUMMARY: The tumor suppressing effect of metformin has been reported, and tumor microenvironment including immune cells contribute to tumor progression in colorectal cancer. However, the effects of metformin on tumor-promoting MDSCs and M2 macrophages and its mechanisms remain unclarified. He...

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Detalles Bibliográficos
Autores principales:	Kang, Joyeon, Lee, Doyeon, Lee, Kyoung Jin, Yoon, Jaepil Eric, Kwon, Ji-Hee, Seo, Yoojeong, Kim, Janghyun, Chang, Shin Young, Park, Jihye, Kang, Eun Ae, Park, Soo Jung, Park, Jae Jun, Cheon, Jae Hee, Kim, Tae Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220791/ https://www.ncbi.nlm.nih.gov/pubmed/35740547 http://dx.doi.org/10.3390/cancers14122881

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