The 26S Proteasome Switches between ATP-Dependent and -Independent Mechanisms in Response to Substrate Ubiquitination

The ubiquitin–proteasome system is responsible for the bulk of protein degradation in eukaryotic cells. Proteins are generally targeted to the 26S proteasome through the attachment of polyubiquitin chains. Several proteins also contain ubiquitin-independent degrons (UbIDs) that allow for proteasomal...

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Detalles Bibliográficos
Autores principales: Manfredonia, Abramo J., Kraut, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220805/
https://www.ncbi.nlm.nih.gov/pubmed/35740875
http://dx.doi.org/10.3390/biom12060750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220805/
https://www.ncbi.nlm.nih.gov/pubmed/35740875
http://dx.doi.org/10.3390/biom12060750

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