Cargando…

The Machine-Learning-Mediated Interface of Microbiome and Genetic Risk Stratification in Neuroblastoma Reveals Molecular Pathways Related to Patient Survival

SIMPLE SUMMARY: Neuroblastoma is a highly heterogeneous malignancy with a wide range of outcomes from spontaneous regression to fatal chemoresistant disease, as currently treated according to the risk stratification of the Children’s Oncology Group (COG), resulting in some high COG risk patients rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xin, Wang, Xiaoqi, Huang, Ruihao, Stucky, Andres, Chen, Xuelian, Sun, Lan, Wen, Qin, Zeng, Yunjing, Fletcher, Hansel, Wang, Charles, Xu, Yi, Cao, Huynh, Sun, Fengzhu, Li, Shengwen Calvin, Zhang, Xi, Zhong, Jiang F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220810/ https://www.ncbi.nlm.nih.gov/pubmed/35740540 http://dx.doi.org/10.3390/cancers14122874

Ejemplares similares

RNA-Sequencing Combined With Genome-Wide Allele-Specific Expression Patterning Identifies ZNF44 Variants as a Potential New Driver Gene for Pediatric Neuroblastoma
por: Sun, Lan, et al.
Publicado: (2023)

BDP1 Variants I1264M and V1347M Significantly Associated with Clinical Outcomes of Pediatric Neuroblastoma Patients Imply a New Prognostic Biomarker: A 121-Patient Cancer Genome Study
por: Li, Xiaoqing, et al.
Publicado: (2021)

Reply to Schramm, L. Comment on “Li et al. BDP1 Variants I1264M and V1347M Significantly Associated with Clinical Outcomes of Pediatric Neuroblastoma Patients Imply a New Prognostic Biomarker: A 121-Patient Cancer Genome Study. Diagnostics 2021, 11, 2364”
por: Li, Xiaoqing, et al.
Publicado: (2022)

Microfluidic enrichment of plasma cells improves treatment of multiple myeloma
por: Zeng, Yunjing, et al.
Publicado: (2018)

Corrigendum to: Microfluidic enrichment of plasma cells improves treatment of multiple myeloma
por: Zeng, Yunjing, et al.
Publicado: (2021)

Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes
por: Stucky, Andres, et al.
Publicado: (2022)

Caveolae-Mediated Extracellular Vesicle (CMEV) Signaling of Polyvalent Polysaccharide Vaccination: A Host–Pathogen Interface Hypothesis †
por: Li, Shengwen Calvin, et al.
Publicado: (2022)

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel
por: Li, Shengwen Calvin, et al.
Publicado: (2018)

Genomic Analysis of Oral Lichen Planus and Related Oral Microbiome Pathogens
por: Zhong, Evelyn F., et al.
Publicado: (2020)

WANTED: Better neuroblastoma biomarkers and better stratification
por: London, Wendy B.
Publicado: (2022)

Improved risk stratification by PET-based intratumor heterogeneity in children with high-risk neuroblastoma
por: Li, Chao, et al.
Publicado: (2022)

Long-term survival with anlotinib as a front-line treatment in an elderly NSCLC patient: A case report
por: Wang, Jingyi, et al.
Publicado: (2023)

Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing
por: Szymansky, Annabell, et al.
Publicado: (2021)

Vertical stratification of the air microbiome in the lower troposphere
por: Drautz-Moses, Daniela I., et al.
Publicado: (2022)

Mastering the craft: Creating an insightful and widely-cited literature review
por: Li, Shengwen Calvin
Publicado: (2023)

Serum Protein N-Glycosylation Signatures of Neuroblastoma
por: Qin, Wenjun, et al.
Publicado: (2021)

Effect of sample stratification on dairy GWAS results
por: Ma, Li, et al.
Publicado: (2012)

Cancer Niche as a Garbage Disposal Machine: Implications of TCM-Mediated Balance of Body-Disease for Treatment of Cancer
por: Li, Shengwen Calvin, et al.
Publicado: (2019)

Microbiome Features Differentiating Unsupervised-Stratification-Based Clusters of Patients with Abnormal Glycometabolism
por: Xu, Ting, et al.
Publicado: (2023)

Expression of two parental imprinted miRNAs improves the risk stratification of neuroblastoma patients
por: Gattolliat, Charles-Henry, et al.
Publicado: (2014)

Bone and bone marrow involvement in neuroblastoma: A case report
por: Huang, Can, et al.
Publicado: (2020)

The oral microbiome of patients with ischemic stroke predicts their severity and prognosis
por: Sun, Wenbo, et al.
Publicado: (2023)

A Novel MRI-Based Risk Stratification Algorithm for Predicting Postoperative Recurrence of Meningioma: More Benefits to Patients
por: Zhang, Rufei, et al.
Publicado: (2021)

Application of amide proton transfer imaging to pretreatment risk stratification of childhood neuroblastoma: comparison with neuron-specific enolase
por: Jia, Xuan, et al.
Publicado: (2023)

16S rRNA and metagenomic shotgun sequencing data revealed consistent patterns of gut microbiome signature in pediatric ulcerative colitis
por: Zuo, Wenxuan, et al.
Publicado: (2022)

Current status and prospects of hematopoietic stem cell transplantation in China
por: Wang, Xiaoqi, et al.
Publicado: (2022)

A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
por: Li, Shengwen Calvin, et al.
Publicado: (2008)

Spatiotemporal switching signals for cancer stem cell activation in pediatric origins of adulthood cancer: Towards a watch-and-wait lifetime strategy for cancer treatment
por: Li, Shengwen Calvin, et al.
Publicado: (2018)

Cancer Subclones Derived from the Patient’s Head and Neck Squamous Cell Carcinoma Tumor Stem Cells for the Screening of Personalized Antitumor Immunotherapy and Chemotherapy
por: Li, Shengwen Calvin, et al.
Publicado: (2018)

Autologous Splenocyte Reinfusion Improves Antibody-Mediated Immune Response to the 23-Valent Pneumococcal Polysaccharide-Based Vaccine in Splenectomized Mice
por: Li, Shengwen Calvin, et al.
Publicado: (2020)

Hunting down the dominating subclone of cancer stem cells as a potential new therapeutic target in multiple myeloma: An artificial intelligence perspective
por: Lee, Lisa X, et al.
Publicado: (2020)

A generalizable and tunable engineered ecosystem provides a clear route to prosperity and well-being to harness the world’s aquatic “blue” food systems to help end hunger: A perspective
por: Li, Shengwen Calvin, et al.
Publicado: (2022)

SIOP‐PODC adapted risk stratification and treatment guidelines: Recommendations for neuroblastoma in low‐ and middle‐income settings
por: Parikh, Nehal S., et al.
Publicado: (2015)

The Interface of Vibrio cholerae and the Gut Microbiome
por: Cho, Jennifer Y., et al.
Publicado: (2021)

A novel clinical tool and risk stratification system for predicting the event-free survival of neuroblastoma patients: A TARGET-based study
por: Li, Mingzhen, et al.
Publicado: (2023)

Therapeutic potential of targeting MYCN: A case series report of neuroblastoma with MYCN amplification
por: Huang, Can, et al.
Publicado: (2020)

Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions
por: Chen, Jiarui, et al.
Publicado: (2023)

Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy
por: Wang, Li, et al.
Publicado: (2008)

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila
por: Wang, Li, et al.
Publicado: (2009)

O-terminated interface for thickness-insensitive transport properties of aluminum oxide Josephson junctions
por: Shan, Zheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_udkprhg5iba024n8h2t87c0ne1