β Cell–specific deletion of Zfp148 improves nutrient-stimulated β cell Ca(2+) responses

Insulin secretion from pancreatic β cells is essential for glucose homeostasis. An insufficient response to the demand for insulin results in diabetes. We previously showed that β cell–specific deletion of Zfp148 (β-Zfp148(KO)) improves glucose tolerance and insulin secretion in mice. Here, we perfo...

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Detalles Bibliográficos
Autores principales: Emfinger, Christopher H., de Klerk, Eleonora, Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donnie S., Simonett, Shane P., Mitok, Kelly A., Wang, Ziyue, Liu, Xinyue, Paulo, Joao A., Yu, Qing, Cardone, Rebecca L., Foster, Hannah R., Lewandowski, Sophie L., Perales, José C., Kendziorski, Christina M., Gygi, Steven P., Kibbey, Richard G., Keller, Mark P., Hebrok, Matthias, Merrins, Matthew J., Attie, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220824/
https://www.ncbi.nlm.nih.gov/pubmed/35603790
http://dx.doi.org/10.1172/jci.insight.154198

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