CD206(+) tumor-associated macrophages cross-present tumor antigen and drive antitumor immunity

In many solid cancers, tumor-associated macrophages (TAM) represent the predominant myeloid cell population. Antigen (Ag) cross-presentation leading to tumor Ag–directed cytotoxic CD8(+) T cell responses is crucial for antitumor immunity. However, the role of recruited monocyte-derived macrophages,...

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Detalles Bibliográficos
Autores principales: Modak, Madhura, Mattes, Ann-Kathrin, Reiss, Daniela, Skronska-Wasek, Wioletta, Langlois, Rebecca, Sabarth, Nicolas, Konopitzky, Renate, Ramirez, Fidel, Lehr, Katharina, Mayr, Tobias, Kind, David, Viollet, Coralie, Swee, Lee Kim, Petschenka, Jutta, El Kasmi, Karim C., Noessner, Elfriede, Kitt, Kerstin, Pflanz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220841/
https://www.ncbi.nlm.nih.gov/pubmed/35503656
http://dx.doi.org/10.1172/jci.insight.155022

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