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Targeting genome integrity dysfunctions impedes metastatic potency in non–small cell lung cancer circulating tumor cell–derived explants

DNA damage and genomic instability contribute to non–small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC metastatic potency and may provide rationale for biolo...

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Detalles Bibliográficos
Autores principales:	Tayoun, Tala, Faugeroux, Vincent, Oulhen, Marianne, Déas, Olivier, Michels, Judith, Brulle-Soumare, Laura, Cairo, Stefano, Scoazec, Jean-Yves, Marty, Virginie, Aberlenc, Agathe, Planchard, David, Remon, Jordi, Ponce, Santiago, Besse, Benjamin, Kannouche, Patricia L., Judde, Jean-Gabriel, Pawlikowska, Patrycja, Farace, Françoise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220846/ https://www.ncbi.nlm.nih.gov/pubmed/35511434 http://dx.doi.org/10.1172/jci.insight.155804

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