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Vertical sleeve gastrectomy induces enteroendocrine cell differentiation of intestinal stem cells through bile acid signaling

Vertical sleeve gastrectomy (VSG) results in an increase in the number of hormone-secreting enteroendocrine cells (EECs) in the intestinal epithelium; however, the mechanism remains unclear. Notably, the beneficial effects of VSG are lost in a mouse model lacking the nuclear bile acid receptor farne...

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Detalles Bibliográficos
Autores principales:	Kim, Ki-Suk, Peck, Bailey C.E., Hung, Yu-Han, Koch-Laskowski, Kieran, Wood, Landon, Dedhia, Priya H., Spence, Jason R., Seeley, Randy J., Sethupathy, Praveen, Sandoval, Darleen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220851/ https://www.ncbi.nlm.nih.gov/pubmed/35503251 http://dx.doi.org/10.1172/jci.insight.154302

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