MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

Aberrant epithelial differentiation and regeneration contribute to colon pathologies, including inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Myeloid translocation gene 16 (MTG16, also known as CBFA2T3) is a transcriptional corepressor expressed in the colonic epithelium. MTG...

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Detalles Bibliográficos
Autores principales: Brown, Rachel E., Jacobse, Justin, Anant, Shruti A., Blunt, Koral M., Chen, Bob, Vega, Paige N., Jones, Chase T., Pilat, Jennifer M., Revetta, Frank, Gorby, Aidan H., Stengel, Kristy R., Choksi, Yash A., Palin, Kimmo, Piazuelo, M. Blanca, Washington, Mary Kay, Lau, Ken S., Goettel, Jeremy A., Hiebert, Scott W., Short, Sarah P., Williams, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220854/
https://www.ncbi.nlm.nih.gov/pubmed/35503250
http://dx.doi.org/10.1172/jci.insight.153045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220854/
https://www.ncbi.nlm.nih.gov/pubmed/35503250
http://dx.doi.org/10.1172/jci.insight.153045

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