A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model

Epileptic seizures are common sequelae of stroke, acute brain injury, and chronic neurodegenerative diseases, including Alzheimer’s disease (AD), and cannot be effectively controlled in approximately 40% of patients, necessitating the development of novel therapeutic agents. Activation of the A1 rec...

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Detalles Bibliográficos
Autores principales: Saggu, Shalini, Chen, Yunjia, Chen, Liping, Pizarro, Diana, Pati, Sandipan, Law, Wen Jing, McMahon, Lori, Jiao, Kai, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220929/
https://www.ncbi.nlm.nih.gov/pubmed/35674133
http://dx.doi.org/10.1172/jci.insight.155002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220929/
https://www.ncbi.nlm.nih.gov/pubmed/35674133
http://dx.doi.org/10.1172/jci.insight.155002

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