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Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives
Background: Recent evidence suggests that a higher body weight may be linked to cognitive impairment in different domains involving executive/frontal functioning. However, challenging results are also available. Accordingly, our study was designed to verify whether (i) poor executive functions are r...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220982/ https://www.ncbi.nlm.nih.gov/pubmed/35741662 http://dx.doi.org/10.3390/brainsci12060777 |
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author | La Marra, Marco Villano, Ines Ilardi, Ciro Rosario Carosella, Mario Staiano, Maria Iavarone, Alessandro Chieffi, Sergio Messina, Giovanni Polito, Rita Porro, Chiara Scarinci, Alessia Monda, Vincenzo Carotenuto, Marco Di Maio, Girolamo Messina, Antonietta |
author_facet | La Marra, Marco Villano, Ines Ilardi, Ciro Rosario Carosella, Mario Staiano, Maria Iavarone, Alessandro Chieffi, Sergio Messina, Giovanni Polito, Rita Porro, Chiara Scarinci, Alessia Monda, Vincenzo Carotenuto, Marco Di Maio, Girolamo Messina, Antonietta |
author_sort | La Marra, Marco |
collection | PubMed |
description | Background: Recent evidence suggests that a higher body weight may be linked to cognitive impairment in different domains involving executive/frontal functioning. However, challenging results are also available. Accordingly, our study was designed to verify whether (i) poor executive functions are related to a higher body weight and (ii) executive functioning could contribute to weight loss in treatment-seeking overweight and obese patients. Methods: We examined general executive functioning, inhibitory control, verbal fluency, and psychomotor speed in a sample including 104 overweight and obese patients. Forty-eight normal-weight subjects participated in the study as controls. Results: Univariate Analysis of Variance showed that obese patients obtained lower scores than overweight and normal-weight subjects in all executive measures, except for errors in the Stroop test. However, when sociodemographic variables entered the model as covariates, no between-group difference was detected. Furthermore, an adjusted multiple linear regression model highlighted no relationship between weight loss and executive scores at baseline. Conclusions: Our results provide further evidence for the lack of association between obesity and the executive domains investigated. Conflicting findings from previous literature may likely be due to the unchecked confounding effects exerted by sociodemographic variables and inclusion/exclusion criteria. |
format | Online Article Text |
id | pubmed-9220982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92209822022-06-24 Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives La Marra, Marco Villano, Ines Ilardi, Ciro Rosario Carosella, Mario Staiano, Maria Iavarone, Alessandro Chieffi, Sergio Messina, Giovanni Polito, Rita Porro, Chiara Scarinci, Alessia Monda, Vincenzo Carotenuto, Marco Di Maio, Girolamo Messina, Antonietta Brain Sci Article Background: Recent evidence suggests that a higher body weight may be linked to cognitive impairment in different domains involving executive/frontal functioning. However, challenging results are also available. Accordingly, our study was designed to verify whether (i) poor executive functions are related to a higher body weight and (ii) executive functioning could contribute to weight loss in treatment-seeking overweight and obese patients. Methods: We examined general executive functioning, inhibitory control, verbal fluency, and psychomotor speed in a sample including 104 overweight and obese patients. Forty-eight normal-weight subjects participated in the study as controls. Results: Univariate Analysis of Variance showed that obese patients obtained lower scores than overweight and normal-weight subjects in all executive measures, except for errors in the Stroop test. However, when sociodemographic variables entered the model as covariates, no between-group difference was detected. Furthermore, an adjusted multiple linear regression model highlighted no relationship between weight loss and executive scores at baseline. Conclusions: Our results provide further evidence for the lack of association between obesity and the executive domains investigated. Conflicting findings from previous literature may likely be due to the unchecked confounding effects exerted by sociodemographic variables and inclusion/exclusion criteria. MDPI 2022-06-14 /pmc/articles/PMC9220982/ /pubmed/35741662 http://dx.doi.org/10.3390/brainsci12060777 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article La Marra, Marco Villano, Ines Ilardi, Ciro Rosario Carosella, Mario Staiano, Maria Iavarone, Alessandro Chieffi, Sergio Messina, Giovanni Polito, Rita Porro, Chiara Scarinci, Alessia Monda, Vincenzo Carotenuto, Marco Di Maio, Girolamo Messina, Antonietta Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title | Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title_full | Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title_fullStr | Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title_full_unstemmed | Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title_short | Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives |
title_sort | executive functions in overweight and obese treatment-seeking patients: cross-sectional data and longitudinal perspectives |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220982/ https://www.ncbi.nlm.nih.gov/pubmed/35741662 http://dx.doi.org/10.3390/brainsci12060777 |
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