Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to intestinal cortisol production (intestinal steroidogenesis), being reduced in UC p...

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Detalles Bibliográficos
Autores principales: Landskron, Glauben, Dubois-Camacho, Karen, Orellana-Serradell, Octavio, De la Fuente, Marjorie, Parada-Venegas, Daniela, Bitrán, Mirit, Diaz-Jimenez, David, Tang, Shuang, Cidlowski, John A., Li, Xiaoling, Molina, Hector, Gonzalez, Carlos M., Simian, Daniela, Lubascher, Jaime, Pola, Victor, Montecino, Martín, Blokzijl, Tjasso, Faber, Klaas Nico, González, María-Julieta, Quera, Rodrigo, Hermoso, Marcela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221003/
https://www.ncbi.nlm.nih.gov/pubmed/35741034
http://dx.doi.org/10.3390/cells11121905

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