A Novel Bispecific T-Cell Engager (CD1a x CD3ε) BTCE Is Effective against Cortical-Derived T Cell Acute Lymphoblastic Leukemia (T-ALL) Cells

SIMPLE SUMMARY: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive and still orphan hematologic malignancy. No effective immunotherapeutic strategies are presently available for this poor prognosis disease. We here report the development and the preclinical evaluation of a novel bispecific...

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Detalles Bibliográficos
Autores principales: Riillo, Caterina, Caracciolo, Daniele, Grillone, Katia, Polerà, Nicoletta, Tuccillo, Franca Maria, Bonelli, Patrizia, Juli, Giada, Ascrizzi, Serena, Scionti, Francesca, Arbitrio, Mariamena, Lopreiato, Mariangela, Siciliano, Maria Anna, Sestito, Simona, Talarico, Gabriella, Galea, Eulalia, Galati, Maria Concetta, Pensabene, Licia, Loprete, Giovanni, Rossi, Marco, Ballerini, Andrea, Gentile, Massimo, Britti, Domenico, Di Martino, Maria Teresa, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221015/
https://www.ncbi.nlm.nih.gov/pubmed/35740552
http://dx.doi.org/10.3390/cancers14122886

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