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Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection
Background: One of the main symptoms of COVID-19 is hyposmia or even anosmia. Olfactory identification is most often affected. In addition, some cognitive disorders tend to appear following the infection, particularly regarding executive functions, attention, and memory. Olfaction, and especially ol...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221020/ https://www.ncbi.nlm.nih.gov/pubmed/35741601 http://dx.doi.org/10.3390/brainsci12060714 |
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author | Fiorentino, Julie Payne, Magali Cancian, Elisa Plonka, Alexandra Dumas, Louise-Émilie Chirio, David Demonchy, Élisa Risso, Karine Askenazy-Gittard, Florence Guevara, Nicolas Castillo, Laurent Robert, Philippe Manera, Valeria Vandersteen, Clair Gros, Auriane |
author_facet | Fiorentino, Julie Payne, Magali Cancian, Elisa Plonka, Alexandra Dumas, Louise-Émilie Chirio, David Demonchy, Élisa Risso, Karine Askenazy-Gittard, Florence Guevara, Nicolas Castillo, Laurent Robert, Philippe Manera, Valeria Vandersteen, Clair Gros, Auriane |
author_sort | Fiorentino, Julie |
collection | PubMed |
description | Background: One of the main symptoms of COVID-19 is hyposmia or even anosmia. Olfactory identification is most often affected. In addition, some cognitive disorders tend to appear following the infection, particularly regarding executive functions, attention, and memory. Olfaction, and especially olfactory identification, is related to semantic memory which manages general knowledge about the world. The main objective of this study was to determine whether semantic memory is impaired in case of persistent post COVID-19 olfactory disorders. Methods: 84 patients (average age of 42.8 ± 13.6 years) with post COVID-19 olfactory loss were included after consulting to the ENT department. The clinical evaluation was carried out with the Pyramid and Palm Tree Test, the word-retrieval task from the Grémots, the Sniffin’ Sticks Test and the Computerised Olfactory Test for the Diagnosis of Alzheimer’s Disease. Results: Semantic memory was impaired in 20% (n = 17) of patients, especially in the 19–39 age-group. The olfactory threshold was only significantly correlated with the semantic memory scores. Conclusions: Similar to all cognitive disorders, semantic disorders can have a negative impact on quality of life if left untreated. It is essential to carry out specific assessments of post COVID-19 patients to accurately determine their disorders and to put in place the best possible rehabilitation, such as speech and language therapy, to avoid quality-of-life impairment. |
format | Online Article Text |
id | pubmed-9221020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92210202022-06-24 Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection Fiorentino, Julie Payne, Magali Cancian, Elisa Plonka, Alexandra Dumas, Louise-Émilie Chirio, David Demonchy, Élisa Risso, Karine Askenazy-Gittard, Florence Guevara, Nicolas Castillo, Laurent Robert, Philippe Manera, Valeria Vandersteen, Clair Gros, Auriane Brain Sci Article Background: One of the main symptoms of COVID-19 is hyposmia or even anosmia. Olfactory identification is most often affected. In addition, some cognitive disorders tend to appear following the infection, particularly regarding executive functions, attention, and memory. Olfaction, and especially olfactory identification, is related to semantic memory which manages general knowledge about the world. The main objective of this study was to determine whether semantic memory is impaired in case of persistent post COVID-19 olfactory disorders. Methods: 84 patients (average age of 42.8 ± 13.6 years) with post COVID-19 olfactory loss were included after consulting to the ENT department. The clinical evaluation was carried out with the Pyramid and Palm Tree Test, the word-retrieval task from the Grémots, the Sniffin’ Sticks Test and the Computerised Olfactory Test for the Diagnosis of Alzheimer’s Disease. Results: Semantic memory was impaired in 20% (n = 17) of patients, especially in the 19–39 age-group. The olfactory threshold was only significantly correlated with the semantic memory scores. Conclusions: Similar to all cognitive disorders, semantic disorders can have a negative impact on quality of life if left untreated. It is essential to carry out specific assessments of post COVID-19 patients to accurately determine their disorders and to put in place the best possible rehabilitation, such as speech and language therapy, to avoid quality-of-life impairment. MDPI 2022-05-31 /pmc/articles/PMC9221020/ /pubmed/35741601 http://dx.doi.org/10.3390/brainsci12060714 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Fiorentino, Julie Payne, Magali Cancian, Elisa Plonka, Alexandra Dumas, Louise-Émilie Chirio, David Demonchy, Élisa Risso, Karine Askenazy-Gittard, Florence Guevara, Nicolas Castillo, Laurent Robert, Philippe Manera, Valeria Vandersteen, Clair Gros, Auriane Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title | Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title_full | Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title_fullStr | Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title_full_unstemmed | Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title_short | Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection |
title_sort | correlations between persistent olfactory and semantic memory disorders after sars-cov-2 infection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221020/ https://www.ncbi.nlm.nih.gov/pubmed/35741601 http://dx.doi.org/10.3390/brainsci12060714 |
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