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Sigma-1 Receptor Modulation by Ligands Coordinates Cancer Cell Energy Metabolism

Sigma-1 receptor (S1R) is an important endoplasmic reticulum chaperone with various functions in health and disease. The purpose of the current work was to elucidate the involvement of S1R in cancer energy metabolism under its basal, activated, and inactivated states. For this, two cancer cell lines...

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Detalles Bibliográficos
Autores principales: Oflaz, Furkan E., Koshenov, Zhanat, Hirtl, Martin, Rost, Rene, Malli, Roland, Graier, Wolfgang F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221035/
https://www.ncbi.nlm.nih.gov/pubmed/35740887
http://dx.doi.org/10.3390/biom12060762