Cargando…

Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

SIMPLE SUMMARY: Catalytically inactive kinases, also named pseudokinases, play important roles in the regulation of cell growth and adhesion. While frequently deregulated in human cancer, their role in tumour development is partially elucidated. Here, we report an important tumour function for the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lecointre, Céline, Fourgous, Elise, Montarras, Ingrid, Kerneur, Clément, Simon, Valérie, Boublik, Yvan, Bonenfant, Débora, Robert, Bruno, Martineau, Pierre, Roche, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221080/ https://www.ncbi.nlm.nih.gov/pubmed/35740644 http://dx.doi.org/10.3390/cancers14122981

Ejemplares similares

SHED-Dependent Oncogenic Signaling of the PEAK3 Pseudo-Kinase
por: Ounoughene, Youcef, et al.
Publicado: (2021)

Regulation of Src tumor activity by its N-terminal intrinsically disordered region
por: Aponte, Emilie, et al.
Publicado: (2022)

Correction to: Regulation of Src tumor activity by its N-terminal intrinsically disordered region
por: Aponte, Emilie, et al.
Publicado: (2022)

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3
por: Torosyan, Hayarpi, et al.
Publicado: (2023)

Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling
por: Roy, Michael J., et al.
Publicado: (2023)

Structure of a pseudokinase domain switch that controls oncogenic activation of Jak kinases
por: Toms, Angela V., et al.
Publicado: (2013)

Hyperactivation of Oncogenic JAK3 Mutants Depend on ATP Binding to the Pseudokinase Domain
por: Raivola, Juuli, et al.
Publicado: (2018)

Tribbles Pseudokinases in Colorectal Cancer
por: Ferreira, Bibiana I., et al.
Publicado: (2021)

What is the point of pseudokinases?
por: Raju, Saravanan, et al.
Publicado: (2015)

Pseudokinase is active after all
por: LeBrasseur, Nicole
Publicado: (2008)

Nucleotide-binding mechanisms in pseudokinases
por: Hammarén, Henrik M., et al.
Publicado: (2016)

Pseudokinases, Tribbles Proteins and Cancer
por: Velasco, Guillermo, et al.
Publicado: (2023)

SCYL pseudokinases in neuronal function and survival
por: Pelletier, Stephane
Publicado: (2016)

Pharmacological Targeting of the Pseudokinase Her3
por: Xie, Ting, et al.
Publicado: (2014)

Pseudokinases-remnants of evolution or key allosteric regulators?
por: Zeqiraj, Elton, et al.
Publicado: (2010)

The real role of pseudokinase: linking diabetes to cancers
por: Li, Ke, et al.
Publicado: (2016)

Tribbles Pseudokinase 3 Regulation and Contribution to Cancer
por: Stefanovska, Bojana, et al.
Publicado: (2021)

STRAD pseudokinases regulate axogenesis and LKB1 stability
por: Veleva-Rotse, Biliana O, et al.
Publicado: (2014)

Perturbations of the ZED1 pseudokinase activate plant immunity
por: Bastedo, D. Patrick, et al.
Publicado: (2019)

Cataloguing the dead: breathing new life into pseudokinase research
por: Shrestha, Safal, et al.
Publicado: (2020)

Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling
por: Raivola, Juuli, et al.
Publicado: (2019)

The Pseudokinase TRIB1 in Immune Cells and Associated Disorders
por: Danger, Richard, et al.
Publicado: (2022)

Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2
por: Byrne, Dominic P., et al.
Publicado: (2023)

Major pathways involved in macrophage polarization in cancer
por: Kerneur, Clément, et al.
Publicado: (2022)

The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer
por: Naudin, Cécile, et al.
Publicado: (2016)

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association
por: Patel, Onisha, et al.
Publicado: (2017)

ROR1 is a pseudokinase that is crucial for MET-driven tumorigenesis
por: Lazzari, Luca, et al.
Publicado: (2013)

Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion
por: Vaynberg, Julia, et al.
Publicado: (2018)

The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation
por: Xu, Haixia, et al.
Publicado: (2019)

Structural basis for protein glutamylation by the Legionella pseudokinase SidJ
por: Adams, Michael, et al.
Publicado: (2021)

Recent advances in targeting protein kinases and pseudokinases in cancer biology
por: Riegel, Kristina, et al.
Publicado: (2022)

Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome
por: Kumar, Gaurav, et al.
Publicado: (2022)

Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila
por: Shekhar, Shashank, et al.
Publicado: (2023)

Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
por: André-Grégoire, Gwennan, et al.
Publicado: (2022)

The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer
por: Yang, Xue, et al.
Publicado: (2023)

A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins
por: Fleckenstein, Martin C., et al.
Publicado: (2012)

The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines
por: Liang, Zhuoyi, et al.
Publicado: (2016)

Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ
por: Sulpizio, Alan, et al.
Publicado: (2019)

Control of Cell Growth and Proliferation by the Tribbles Pseudokinase: Lessons from Drosophila
por: Dobens, Leonard L., et al.
Publicado: (2021)

Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
por: Virtanen, Anniina T., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8qdh6i40gipk75e7stcllqbgia