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The Homologous Recombination Deficiency Scar in Advanced Cancer: Agnostic Targeting of Damaged DNA Repair

SIMPLE SUMMARY: Tumor-suppressor genes are involved in DNA break repair through the homologous recombination system and are widely known for their role in hereditary cancer. Beyond breast and ovarian cancer, prostate and pancreatic cancer also have targetable homologous recombination deficiency (HRD...

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Detalles Bibliográficos
Autores principales:	Pacheco-Barcia, Vilma, Muñoz, Andrés, Castro, Elena, Ballesteros, Ana Isabel, Marquina, Gloria, González-Díaz, Iván, Colomer, Ramon, Romero-Laorden, Nuria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221128/ https://www.ncbi.nlm.nih.gov/pubmed/35740616 http://dx.doi.org/10.3390/cancers14122950

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