Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon is a well-established inhibitor of autophagy in all cells. However, Rubicon pa...

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Detalles Bibliográficos
Autores principales: Espinoza, Sandra, Grunenwald, Felipe, Gomez, Wileidy, García, Felipe, Abarzúa-Catalan, Lorena, Oyarce-Pezoa, Sebastián, Hernandez, Maria Fernanda, Cortés, Bastián I., Uhrig, Markus, Ponce, Daniela P., Durán-Aniotz, Claudia, Hetz, Claudio, SanMartín, Carol D., Cornejo, Victor H., Ezquer, Fernando, Parra, Valentina, Behrens, Maria Isabel, Manque, Patricio A., Rojas-Rivera, Diego, Vidal, René L., Woehlbier, Ute, Nassif, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221152/
https://www.ncbi.nlm.nih.gov/pubmed/35740989
http://dx.doi.org/10.3390/cells11121860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221152/
https://www.ncbi.nlm.nih.gov/pubmed/35740989
http://dx.doi.org/10.3390/cells11121860

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