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Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon is a well-established inhibitor of autophagy in all cells. However, Rubicon pa...

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Detalles Bibliográficos
Autores principales:	Espinoza, Sandra, Grunenwald, Felipe, Gomez, Wileidy, García, Felipe, Abarzúa-Catalan, Lorena, Oyarce-Pezoa, Sebastián, Hernandez, Maria Fernanda, Cortés, Bastián I., Uhrig, Markus, Ponce, Daniela P., Durán-Aniotz, Claudia, Hetz, Claudio, SanMartín, Carol D., Cornejo, Victor H., Ezquer, Fernando, Parra, Valentina, Behrens, Maria Isabel, Manque, Patricio A., Rojas-Rivera, Diego, Vidal, René L., Woehlbier, Ute, Nassif, Melissa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221152/ https://www.ncbi.nlm.nih.gov/pubmed/35740989 http://dx.doi.org/10.3390/cells11121860

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