Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present

Ribonucleotide reductase (RR) is an essential multi-subunit enzyme found in all living organisms; it catalyzes the rate-limiting step in dNTP synthesis, namely, the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. As expression levels of human RR (hRR) are high during c...

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Detalles Bibliográficos
Autores principales: Huff, Sarah E., Winter, Jordan M., Dealwis, Chris G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221315/
https://www.ncbi.nlm.nih.gov/pubmed/35740940
http://dx.doi.org/10.3390/biom12060815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221315/
https://www.ncbi.nlm.nih.gov/pubmed/35740940
http://dx.doi.org/10.3390/biom12060815

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